A cross-sectional study was conducted in sheep and goats to determine the prevalence of fasciolosis in and around Mekelle, Tigray Regional State, Ethiopia. Faecal sample collected from a total of 412 small ruminants comprising of 259 sheep and 153 goats were examined by using the sedimentation technique to find out the eggs of Fasciola species. Out of the total, 412 examined faecal samples 67 were found positive for fasciolosis with an overall prevalence rate of 16.3 percent. The prevalence of fasciolosis was higher in sheep (22.8%) as compared to goats (5.2%). Regarding to the occurrence of Fasciola spp. between the animal species there was statically significant (P<0.05)difference between sheep and goats. Also, on body conditions of the animal, the fasciolosis was significantly (P<0.05) higher in poor body followed by medium and good body conditions, respectively. However, the prevalence of fasciolosis between male and female as well as young and adult animals was not statistically significant (p>0.05) difference. The result among the origins of the animals also revealed that there were not statistically significance (p>0.05) difference. This study indicated that fasciolosis to be the major parasitic health problem between the species and also which reduce the body condition of small ruminants. As our recommendation, it needs further investigation to reduce the impact of the disease on animal production and economic values with implementations of successful interventional strategies.

Keywords: Fasciolosis, Goats, Mekelle, Sedimentation, Sheep