Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2758

Full Length Research Paper

Low and high ω-3 oils consequences rats’ serum lipid fractions

Mohammed A. T. Abdelreheem1,2*, Fawzy M. Lashin3, Emad M. El-Kholie4and Amal A. Fatani5
  1Research Center, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Kingdom of Saudi Arabia. 2Biochemistry Department, Faculty of Agriculture, Ain Shams University, Cairo, Egypt. 3National Organization for Drugs Control and Research, Cairo, Egypt. 4Nutrition and Food Science Department, Faculty of Home Economics, Menufiya University, Egypt. 5Pharmacology and Toxicology Department, College of Pharmacy, King Saud University, Kingdom of Saudi Arabia.
Email: [email protected]

  •  Accepted: 07 May 2012
  •  Published: 23 May 2012



To study the consequences of some low and high ω-3 edibles oils on fatty acid profile, triacylglycerols and cholesterol levels of rats’ serum; males of albino rat were fed on diet containing 5 and 10% from each of linseed, safflower and olive oils individually for 4 weeks. The extracted oils and serum lipids were directed togas chromatography (GC) analysis. Serum triacylglycerols and total cholesterol were measured. Feeding rats on 5% olive oil for 4 weeks increased ω-6 monounsaturated fatty acid in serum lipid compared with other tested oils. Contrary relationship between oleic and palmetic acids in rat serum was found. Serum ω-6 di-unsaturated and ω-3 tri-unsaturated fatty acids were decreased in all treatments. Feeding rats on diets containing 5% ω-3 rich oil (linseed) was more effective in lowering the increase of serum triacylglycerol (TAG), while feeding on 10% linseed oil decreased total cholesterol levels compared with other oils. Generally, rats fed with ω-3 rich oil recorded the lowest TAG and total cholesterol levels during all feeding periods compared with other tested lower ω-3 oils.


Keywords: Omega-3 fatty acids, serum lipids, rats.