Abstract

The aim of this study is to determine the effects of the combined testosterone and nandrolone usages, which are frequently use in athletetics was tested on the femur bone of rabbits. Sixty day old twenty-four New Zealand White rabbits were used. Male and female rabbits were divided into two groups as control group (no application) testosterone (10 mg/kg, IM, one day in a week during 12 weeks) + 10 mg/kg nandrolone deaconate (10 mg/kg, IM, one day in a week during 12 weeks). Back extremity bones of materials were revealed by making diseke and were subjected to maceration operation. Combined testosterone and nandrolone usage depressed (p<0.05) the growth of femur length in males compared to the other groups. Although, the drugs depressed the growth of femur length in females, it was no statistically significant. Effects of drugs on the diameters of corpus, cortex thickness and caliber of cavum medulla were no statistically significant (p>0.05). In conclusion, while the combined nandrolone and testosterone usage on males has suspended the growth of the femur bone significantly, the same effects has not been found significant on females compared to males.

Key words: nandrolone, testosterone, morphometric, femur.