Water and methanol extracts of the stem bark of Ficus glumosa were screened for their antimicrobial properties against Salmonella species. Preliminary results showed that the active compound was in the water extract. Therefore, the water extracts (hot and cold) were subjected to column chromatographic fractions and antibacterial screening. The most active fraction was subjected to phytochemical screening and finally Gas Chromatography Mass Spectrography (GC/MS) analysis. The result indicated that the most active fraction was the 3rd hot water extract and its GC/MS analysis was narrowed down to 3,3’-(4-methyl-1,3-phenylene)bis(1-heptylurea), isothujol and Terbuthyl azine.
Key words: Phytochemical screening, Ficus glumosa, column chromatography and antimicrobial activity.