Proceedings

 

39th CSN Annual International Conference

Isolation and characterization of 2, 4-dihydroxycinnamic acid from the stem bark of Adina microcephala Delile

Ayo, S. G.
  • Ayo, S. G.
  • College of Agriculture, Ahmadu Bello University, Zaria, Kaduna State, Nigeria
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Habila, J. D.
  • Habila, J. D.
  • Department of Chemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
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Achika, J. I.
  • Achika, J. I.
  • Department of Chemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
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Akinwande, O. O.
  • Akinwande, O. O.
  • Department of Chemistry, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.
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  • Article Number - 47BCC70

Abstract

Adina microcephala which belongs to the family Rubiaceae is widely distributed in Africa. It is used in African traditional medicine for the treatment of diarrhoea and other stomach or digestive tract problems. A microcephala stem bark was collected, identified, dried and pulverized. The pulverized plant material was subjected to Soxhlet extraction using petroleum ether (60-80°C), chloroform, ethyl acetate and methanol. The ethyl acetate extract was subjected to further purification by chromatographic techniques to yield a compound labeled R1 which was then fully characterized as 2, 4-dihydroxycinnamic acid using IR, 1D and 2D NMR spectroscopic techniques.

 

Key words: 2,4-Dihydroxycinnamic acid, Adina microcephala, Rubiaceae, stem bark.

 

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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