Abstract

The objective of this study was to examine the in vitro antitumour activities of Lentinus edodes polysaccharides. The present results demonstrated that L. edodespolysaccharides at 100 and 200 mg/kg dose-dependently suppressed liver tumour growth. The polysaccharides were still found to be dose-dependently and enhance spleen and thymus index and inhibit expression of Caspase-3 in mice with liver cancer. It may be concluded that L. edodes polysaccharides is beneficial to therapy of liver tumour.

Key words: Liver cancer, Lentinus edodes polysaccharides, caspase-3, spleen index.