As a result of working conditions, a variety of variables lead to the development of occupational health and safety impairments such as injuries and musculoskeletal disorders among sanitary personnel, which must be identified in order to anticipate concerns. PubMed, Medline, Embase, and Lilacs databases were used from 2000 to April 2022. Searched strategies used logical words “AND/OR”: Occupational *OR Work AND Injuries OR Musculoskeletal Disorder AND Associated Factors [Socio-demographic *OR Behavioral factors *OR Institution Factors *OR Work pattern] AND Sanitary workers [Waste collectors and emptier *OR Street Sweepers *OR Sewage workers *OR Health facilities] AND Countries [Developed *OR Developing] From total of 78 eligible, 13 studies on were included in this review. The majority of the 4564 sanitary personnel, 3844 (84%) were solid waste collectors. The rest are street sweepers 10% (450) and cleaners 6% (270). Age (OR: 22.57; CI95%:7.29-69.88); education (OR: 2.22; CI95%:1.22-4.00); and experience (OR: 1.92; CI95% 1.11-3.31) were the significant predictors for occurrence of occupational injuries. Smoking cigarettes (OR:2.6, CI95%:1.55-4.34); sleeping disturbance (OR:2.57, CI95%:1.48-4.47); eating/smoking/drinking at work (OR:3.85, CI95%: 1.34-11.06); and lack of personal protective equipment (OR: 2.62; 1.48-4.63) are the other predictors. On other side, Education (OR:6.73; CI95%:1.92-23.51), age (OR: 7.56; CI95%:2.18-26.18), and job experience (OR:10.79; CI95%:3.49-33.38) are socio-demographic variables that impact the development of musculoskeletal disorders. Cigarette smoking (OR: 0.14; CI95%:0.03-0.64) and job satisfaction (OR: 11.43; CI95%:2.04-64.08) are behavioral factors. While, working longer than 8 hours (OR: 3.5; CI95%:1.543-8.204) and time pressure (OR: 3.25; CI95%:1.08-9.77), working for more than 2 hours (OR: 8; CI95%: 2.25; 28.85) and having a bad back (OR: 15.7; CI95%: 6.47-38.18) are the other risk factors for MSDs. According to current reviewed evidence, socio-demographic indicators, occupational safety with work pattern features, and behavioral factors all significantly contributed to musculoskeletal disorders; occupational injuries among sanitation workers, which require emphasis from government policy and other initiatives.

Keywords: Disorder, Factors; Injuries; Musculoskeletal; Occupational; Review; Sanitary; workers