This study was designed to determine the effect of Lycium barbarumpolysaccharides (LBP) on physical fatigue in mice. 96 male Balb/c mice were divided randomly into four groups based on body weight. One of the group was the control group, the others were LBP treated groups (100, 200, 400 mg/kg body weight). Forced swimming test of mice were carried out after 28 days of LBP administration, and the blood lactate and tissue glycogen contents were determined. Results showed that LBP can extend the swimming time of the mice, effectively delay the increasing of lactate in the blood, and promotes sparing of glycogen. It suggested that LBP contributes to enhancement of physical strength and ameliorates physical fatigue.
Key words: Lycium barbarum polysaccharides, physical fatigue, mice.
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