African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Short Communication

Phytochemical analysis and antimicrobial screening of crude extracts from the leaves, stem bark and root bark of Ekebergia senegalensis A. Juss

Ndukwe, I. G.*, Habila, J. D., Bello, I. A. and Adeleye, E.O.
Department of Chemistry, Ahmadu Bello University, Samaru, Zaria, Nigeria.
Email: [email protected]

  •  Accepted: 25 August 2006
  •  Published: 02 October 2006

Abstract

The leaves, stem bark and root bark of Ekebergia senegalensis, which has some traditional medicinal applications were investigated. Phytochemical analysis gave positive results for carbohydrates, glycosides, saponins, tannins and alkaloids. The crude methanol extracts showed growth inhibitory effects on Salmonella typhi,Pseudomonas, Klebsiella, Bacillus subtilis, Escherichia coli andStaphylococcus aureus. The minimum inhibitory concentration (MIC) of these extracts on the bacteria is 0.125 x 103 mg/ml for the methanol extracts. The minimum bactericidal concentration (MBC) determination showed that a concentration of 0.03125 x 103 mg/ml of the methanol extract of the leaves could completely kill S. typhi. The petroleum spirit extract did not show marked antimicrobial activity.

 

Key words: Ekebergia senegalensis, Maliaceae family, Phytochemical analysis, crude extracts, Antibacterial screening.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 5 No. 19
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES