African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12488

Full Length Research Paper

Prevalence of hepatitis B in the blood donors of N-W.F.P and FATA regions and the current scenario of HBV infection in Pakistan

Najib Ullah Khan1, Lubna Siddique1, Ijaz Ali1*, Aqib Iqbal1, Iqbal Munir1, Farzana Rashid2, Sajid Ali3, Fazal Raziq4 and Zahoor Ahmad Swati1
1Institute of Biotechnology and Genetic Engineering N.W.F.P Agricultural University Peshawar, Pakistan. 2Lahore College for Women University, Lahore, Pakistan. 3Department of Biotechnology, Peshawar University, Pakistan. 4Hayat Abad Medical Complex, Peshawar, Pakistan.
Email: [email protected]

  •  Accepted: 05 May 2010
  •  Published: 13 September 2010

Abstract

Hepatitis B is a fatal liver disease caused by the hepatitis B virus. In this study, blood donors from various districts of the North-western frontier province and the federally administered tribal area (FATA) of Pakistan were tested for HBsAg and HBV DNA by ICT (Immuno-chromatographic test), ELISA and RT-PCR. Out of the 7148 blood donors, 244 (3.41%) were positive for HBsAg by ICT, 147 (2.05%) by ELISA while 132 (1.85%) were positive by PCR. Our data indicates that the incidence of hepatitis B has decreased in these regions in recent times.

 

Key words: HBV, HBsAg, Pakistan.

Abbreviation

FATA, Federally administered tribal area; ELISA, enzyme-linked immunosorbent assay; PCR, polymerase chain reaction; RT-PCR, reverse transcriptase- PCR; HBV, hepatitis B virus; HBsAg, hepatitis B antigen; ICT,immuno-chromatographic test.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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