Abstract

The purpose of this study is to demonstrate the effects of glutamine (Gln) supplement on small intestinal morphology, xylose absorptive and growth performance of weaned piglets. Forty eight piglets weaned at 28 ± 2 days of age were randomly allotted to three treatment groups. A basal corn-soybean diet was formulated to contain 20.3% protein and 3450 kcal DE/kg diet. Glutamine was supplemented to the basal diet at 0% (control), 1% (Gln 1%) and 2% (Gln 2%). Pigs were fed experimental diets for three weeks. The results showed that the villous height of the Gln groups tended higher than the control group in duodenum and jejunum (P < 0.1). Glutamine supplementation increased plasma net xylose absorptive concentration from 0.78 to 1.20 and 0.95 to 1.23 in Gln 1% and Gln 2% group, respectively, which were better than the control group (0.86 to 0.97) in day 7 to 14 after weaning. Growth performance was not significantly affected by Glnsupplement; however, average daily gain was approximately improved from 21 to 28% by Gln supplement compared to the control group during 21 days of experimental period. In summary, the results suggested that dietary supplementation of Gln could be beneficial in small intestinal villous morphology and xylose absorptive capacity, and could have a slight contribution to the average daily gain of weaned piglets.

Key words: Glutamine, growth performance, intestinal morphology, weaned piglets.

Abbreviation

Gln, Glutamine;  P5C, proline 5-carboxylate; DE, digestible energy;CP, crude protein; SI, small intestine; PBS, phosphate buffered saline; EDTA,ethylenediaminetetraacetic acid;; TPN, total parenteral nutrition; IgA,immunoglobulin A; VH, villous height; CD, crypt depth; BW, body weight; ADG,average daily gain; ADFI, average daily feed intake.