African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12294

Full Length Research Paper

Antioxidant, cytotoxic and antimicrobial activities of Dendropanax morbifera and sweet potato extracts for production of health-oriented food materials

Kibeom Lee
  • Kibeom Lee
  • Bioindustry Center, lncheon Technopark, 12 Gaetbeol-ro, Yeonsu-gu, lncheon, South Korea 21999.
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Ju Hyun Park
  • Ju Hyun Park
  • Genetrone Biotech Co., Ltd, 2F, 4F, Sehyun Building, 15 Hongsanbuk-ro, Wansan-gu, Jeonju-si Jeollabuk-do, South Korea.
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Yun Sung Kim
  • Yun Sung Kim
  • Genetrone Biotech Co., Ltd, 2F, 4F, Sehyun Building, 15 Hongsanbuk-ro, Wansan-gu, Jeonju-si Jeollabuk-do, South Korea.
  • Google Scholar


  •  Received: 21 March 2020
  •  Accepted: 04 May 2020
  •  Published: 31 May 2020

Abstract

The antioxidant, cytotoxic and antimicrobial effects of fermented and non-fermented extracts of ‘the Korean shrub’ Dendropanax morbifera and sweet potato were compared to assess the potential utility of these species in the development of health-oriented food. Non-fermented extract (NFDSE) was obtained from the leaves and branches of D. morbifera and the bodies of sweet potato using distilled water. The fermented extract (FDSE) was prepared by inoculating the above-obtained extracts with Lactobacillus plantarum and Lactobacillus brevis. The extracts of the two species combined D. morbifera and sweet potato exhibited substantial antioxidant activity. Moreover, NFDSE at 24 h exerted more antioxidant effects than FDSE (72.57% vs. 71.08%, respectively) at a concentration of 100 mg/ml. Comparison of the effects of the non-fermented and fermented extracts on HaCaT keratinocyte cell viability revealed that FDSE had a slightly higher cytotoxicity than NFDSE (94.8% vs. 102.7% viability, respectively) at a concentration of 500 g/ml. It was further found that NFDSE and FDSE had the strongest antimicrobial effects against Staphylococcus aureus ATCC 25923 and Staphylococcus epidermidis (a Gram-positive coccidium). Therefore, it is obvious that extracts of D. morbifera and sweet potato represent ‘novel candidates’ for the production of functional anti-aging agents with minimal side effects.
 
Key words: Dendropanax morbifera and sweet potato, antioxidant activity, cytotoxicity, antimicrobial effects, health-oriented food.