African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12486

Full Length Research Paper

Special variations within 11.7 kb fragment in goat polled intersex syndrome

  Xianglong Li*, Jingjing Zhang, Rongyan Zhou, Lanhui Li and Guiru Zheng
College of Animal Science and Technology, Agricultural University of Hebei, Baoding 071001, China.
Email: [email protected]

  •  Accepted: 25 March 2011
  •  Published: 13 July 2011

Abstract

 

The goat polled intersex syndrome (PIS) is a full association between the absence of horns and intersexuality. Several pairs of primer were designed to detect the complete or partial deletion of 11.7 kb fragment in PIS goat. We proved that the 11.7 kb fragment was not deleted completely but partially in PIS goat. The special 198 base substitutions were found between normal and PIS dairy goats, which formed haplotypes A and B, representing normal and PIS dairy goat, respectively. Another special variation was the 18 deletions forming 108 bases deletion that only exist inPIS dairy goat. It could be inferred that the special 198 base substitutions and 108 bases deletion might be triggered intersexuality in the dairy goat.

 

Key words: Polled intersex syndrome (PIS) dairy goat, special base substitutions, special bases deletion.