African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Preliminary study into the long term effects of a hypoglycaemic polyherbal formula (Yem-Kem) on some biochemical parameters in normal rabbits

Ojekale, A. B.1*, Kappo, M. A.1, Agbasoro, S.2 and Kazeem, A.2
  1Department of Biotechnology, University of the Western Cape, Bellville, Cape Town, South Africa. 2Department of Biochemistry, Lagos State University, Ojo, P.M.B.001, Apapa, Lagos, Nigeria.
Email: [email protected]

  •  Accepted: 27 October 2007
  •  Published: 16 May 2008

Abstract

 

The blood glucose lowering capacity of the polyherbal formula (Yem-Kem) was investigated in this study in an in vivo clinical trial using normal Sprague-Dawley rabbits orally administered with the formula over a 60 day period. The results showed that continuous exposure to the extract resulted in an overall lowered blood glucose level, lowered body weight and serum triglycerides, an increased alkaline phosphatase level, and fairly stable bilirubin levels. The formula is efficient as a hypoglycemic formulation, but its toxicity or otherwise cannot be established by this study.

 

Key words: Hypoglycaemia, serum analytes, enzymes, herbal formula, Yem-Kem.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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