African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Preliminary phytochemical and antimicrobial screening of 50 medicinal plants from Nigeria

D. Kubmarawa1*, G. A. Ajoku2, N. M. Enwerem3 and D. A. Okorie4
  1Department of Chemistry, Federal University of Technology, P. M. B. 2076, Yola, Adamawa State, Nigeria. 2Department of Pharmaceutical Microbiology, National Institute for Pharmaceutical Research and Development Abuja, Nigeria. 3Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria. 4Department of Chemistry, University of Ibadan, Ibadan, Nigeria.
Email: [email protected]

  •  Accepted: 15 June 2007
  •  Published: 18 July 2007

Abstract

 

Ethanolic extracts of 50 plant species were screened for their antimicrobial activity against Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. The results indicated that of the 50 plant extracts, 28 plant extracts inhibited the growth of one or more test pathogens. Four plant extracts showed a broad spectrum of antimicrobial activity. Phytochemical investigation revealed the presence of tannins, saponins, alkaloids, glycosides, flavonoids and essential oils.

 

Key words: Medicinal plant, antimicrobial activity, phytochemical, ethnomedicinal

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This article is published under the terms of the Creative Commons Attribution License 4.0

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