African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12486

Full Length Research Paper

Antibiotic and surfactant effects on lysine accumulation by Bacillus megaterium

I. A. Ekwealor1* and J. A. N. Obeta2
  1Department of Applied Microbiology and Brewing, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria. 2Department of Microbilology, University of Nigeria, Nsukka, Enugu State, Nigeria.
Email: [email protected]

  •  Accepted: 29 January 2008
  •  Published: 16 May 2008

Abstract

 

The effects of antibiotics and surfactants on lysine accumulation in the culture broth of three strains of Bacillus megaterium (B. megaterium SP 86, B.megaterium SP 76 and B. megaterium SP 14) were investigated. Lincomycin, neomycin and tetracycline stimulated lysine increase in B. megaterium SP 76 andB. megaterium SP 14, while erythromycin enhanced lysine yield in all three strains. Palmitic acid improved lysine accumulation in B. megaterium SP 86 and B. megaterium SP 14. However, Tween 80 and linoleic acid stimulated lysine increase in B. megaterium SP 76.

 

Key words: L-Lysine, antibiotics, surfactants, Bacillus megaterium, culture broth.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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