Improved affinity of a chicken single-chain antibody to avian infectious bronchitis virus by site-directed mutagenesis of complementarity-determining region H3

Yuan Lin; Benqiang Li; Man Wang; Rui Jia; Jianhua Wang; Ying Zhang; Jianguo Zhu

doi:10.5897/AJB11.2640

African Journal of
Biotechnology

Abbreviation: Afr. J. Biotechnol.
Language: English
ISSN: 1684-5315
DOI: 10.5897/AJB
Start Year: 2002
Published Articles: 12487

Full Length Research Paper

Improved affinity of a chicken single-chain antibody to avian infectious bronchitis virus by site-directed mutagenesis of complementarity-determining region H3

Yuan Lin1,2, Benqiang Li2, Man Wang2, Rui Jia2, Jianhua Wang1, Ying Zhang3and Jianguo Zhu2*

1Department of Internal Medicine, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling712100, People’s Republic of China. 2School of Agriculture and Biology, Shanghai Key Lab of Veterinary Biology, Shanghai Jiaotong University, Shanghai 200240, People’s Republic of China. 3Raybiotech Inc, 3607 Parkuay Lare, Suit 200, Norcross GA, USA 30092.
Email: [email protected]

Article Number - AE6303B35322
Vol.10(79), pp. 18294-18303 , December 2011
https://doi.org/10.5897/AJB11.2640

Accepted: 31 October 2011
Published: 12 December 2011

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