African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 425

Full Length Research Paper

Insulin resistance and specific biomarkers in blood and urine of type 2 diabetic patients with or without nephropathy in Basrah, Iraq

Adnan Jassim Mohammed Al-Fartosy
  • Adnan Jassim Mohammed Al-Fartosy
  • Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq.
  • Google Scholar
Nadhum Abdulnabi Awad
  • Nadhum Abdulnabi Awad
  • Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq.
  • Google Scholar
Sadoun Abbas Alsalimi
  • Sadoun Abbas Alsalimi
  • Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq.
  • Google Scholar


  •  Received: 03 July 2020
  •  Accepted: 09 September 2020
  •  Published: 31 October 2020

References

American Diabetes Association (ADA) (2018). Diabetes Care. Introduction: Standards of Medical Care in Diabetes 41(Supplement 1):S1-S2.
Crossref

 

Al-Fartosy AJM, Awad NA, Abdalemam DJ (2017a). Biochemical study of the effect of insulin resistance on adiponectin, lipid profile and some antioxidants elements with relation to obesity in type 2 diabetic patients/Basrah-Iraq. American Journal of Biochemistry 7(4):73-82.

 
 

Al-Fartosy AJM, Awad NA, Alsalimi SA (2020a). Osteoprotegerin and Some Trace Elements in Type 2 Diabetic Patients with or without Nephropathy: Effect of Insulin Resistance. International Medical Journal 25(4):1771-1784.

 
 

Al-Fartosy AJM, Awad NA, Mahmood RA (2019). A Comparative Study of Leptin, Oxidant/Antioxidant Status and Some Trace Elements in Women of Healthy Control and Unexplained Infertility in Basrah-Iraq. The Indonesian Biomedical Journal 11(3):327-337.
Crossref

 
 

Al-Fartosy AJM, Awad NA, Mohammed AH (2020b). Intelectin-1 and Endocrinological Parameters in Women with Polycystic Ovary Syndrome: Effect of Insulin Resistance. The Ewha Medical Journal 43(1):1-11.
Crossref

 
 

Al-Fartosy AJM, Mohammed IM (2017). Comparison of Insulin Resistance, Prolactin and HbA1c with Relation to Obesity in Men and Women of Healthy Control and Diabetic Patients / Meisan-Iraq. International Journal of Current Research 9(8):55643-55648.

 
 

Al-Fartosy AJM, Shanan SK, Awad NA (2017b). Biochemical Study of the Effects of Some Heavy Metals on Oxidant / Antioxidant Status in Gasoline Station Workers /Basra-Iraq. International Journal of Scientific and Research Publications 7(2):83-94.

 
 

Bae JC, Lee WY, Yoon KH, Park JY, Son HS, Han KA, Lee KW, Woo JT, Ju YC, Lee WJ, Cho YY, Lee MK (2015). Improvement of Nonalcoholic Fatty Liver Disease With Carnitine-Orotate Complex in Type 2 Diabetes (CORONA): A Randomized Controlled Trial. Diabetes Care 38(7):1245-1252.
Crossref

 
 

Bernardi S, Bossi F, Toffoli B, Fabris B (2016). Roles and Clinical Applications of OPG and TRAIL as Biomarkers in Cardiovascular Disease. BioMed Research International 2016:1-12.
Crossref

 
 

Boughton CK, Munro N, Whyte M (2017). Targeting beta-cell preservation in the management of type 2 diabetes. The British Journal of Diabetes 17(4):134-144.
Crossref

 
 

Campion CG, Sanchez-Ferras O, Batchu SN (2017). Potential Role of Serum and Urinary Biomarkers in Diagnosis and Prognosis of Diabetic Nephropathy. Canadian Journal of Kidney Health and Disease 4:1-18.
Crossref

 
 

Chen M, Xia J, Pei G, Zhang Y, Wu S, Qin Y, Deng Y, Guo S, Guo Y, Xu G, Han M (2016). A more accurate method acquirement by a comparison of the prediction equations for estimating glomerular filtration rate in Chinese patients with obstructive nephropathy. BMC Nephrology 17(1):150.
Crossref

 
 

Cicero AF, Rosticci M, Parini A, Morbini M, Urso R, Grandi E, Borghi C (2015). Short-term effects of a combined nutraceutical of insulin-sensitivity, lipid level and indexes of liver steatosis: a double-blind, randomized, cross-over clinical trial. Nutrition Journal 14(1):1-6.
Crossref

 
 

Debbarma B, Debbarma R, Pegu AK (2015). Significance of Microalbuminuria in Newly Diagnosed type 2 Diabetes Mellitus. IOSR Journal of Dental and Medical Sciences 14(8):40-47.

 
 

Drosos G, Ampatzidou F, Sarafidis P, Karaiskos T, Madesis A, Boutou AK (2018). Serum Creatinine and Chronic Kidney Disease-Epidemiology Estimated Glomerular Filtration Rate: Independent Predictors of Renal Replacement Therapy following Cardiac Surgery. American Journal of Nephrology 48(2):108-117.
Crossref

 
 

Elnajjar MM, Dawood AE, Abu Salem M, Kasemy ZA, Nohman OT /(2016). Diabetic nephropathy among diabetic patients attending El Mahalla General Hospital. Journal of The Egyptian Society of Nephrology and Transplantation 16(1):39-43.
Crossref

 
 

El-Sayed MS, El Badawy A, Abdelmoneim RO, Mansour AE, Khalil MEM, Darwish K (2018). Relationship between serum sialic acid concentration and diabetic retinopathy in Egyptian patients with type 2 diabetes mellitus. Benha Medical Journal 35(2):257-263.
Crossref

 
 

Febbraio M (2017). Health benefits of exercise - more than meets the eye! Nature Reviews Endocrinology 13:72-74.
Crossref

 
 

Fiseha T, Tamir Z (2016). Urinary Markers of Tubular Injury in Early Diabetic Nephropathy. International Journal of Nephrology 2016:1-10.
Crossref

 
 

Giudetti AM, Stanca E, Siculella L, Gnoni GV, Damiano F (2016). Nutritional and hormonal regulation of citrate and carnitine/acylcarnitine transporters: two mitochondrial carriers involved in fatty acid metabolism. International Journal of Molecular Sciences 17(6):1-15.
Crossref

 
 

Indriani V, Lestari T, Dewantari V (2020). Duration of diabetes as an important risk factor of microalbuminuria in type 2 diabetes. Universa Medicina 39(1):42-46.
Crossref

 
 

Jerums G, Ekinci E, Panagiotopoulos S, MacIsaac RJ (2012). Early Glomerular Filtration Rate Loss as a Marker of Diabetic Nephropathy. European Endocrinology 8(1):27-31.
Crossref

 
 

Kim MR, Yu SA, Kim MY, Choi KM, Kim CW (2014). Analysis of glycated serum proteins in type 2 diabetes patients with nephropathy. Biotechnology and Bioprocess Engineering 19 (1):83-92.
Crossref

 
 

Lee SY, Choi ME (2015). Urinary biomarkers for early diabetic nephropathy: beyond albuminuria. Paediatric Nephrology 30(7):1063-1075.
Crossref

 
 

Lim AKH (2014). Diabetic nephropathy - complications and treatment. International Journal of Nephrology And Renovascular Disease 7:361-381.
Crossref

 
 

Mahfouz MH, Assiri AM, Mukhtar MH (2016). Assessment of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Retinol-Binding Protein 4 (RBP4) in Type 2 Diabetic Patients with Nephropathy. Biomarker Insights 11:31-40.
Crossref

 
 

Mise K, Ueno T, Hoshino J, Hazue R, Sumida K, Yamanouchi M, Hayami N, Suwabe T, Hiramatsu R, Hasegawa E, Sawa N, Fujii T, Hara S, Wada J, Makino H, Takaichi K, Ohashi K, Ubara Y (2017). Nodular lesions in diabetic nephropathy: Collagen staining and renal prognosis. Diabetes Research and Clinical Practice 127:187-197.
Crossref

 
 

Park SK, Ryoo JH, Oh CM, Choi JM, Jung JY (2018). Longitudinally evaluated the relationship between body fat percentage and the risk for type 2 diabetes mellitus: Korean Genome and Epidemiology Study (KoGES). European Journal of Endocrinology 178(5):513-521.
Crossref

 
 

Sekulic SP, Sekulic M (2015). Rheological Influence Upon the Glomerular Podocyte and Resultant Mechanotransduction. Kidney and Blood Pressure Research 40(2):176-187.
Crossref

 
 

Sirivole MR, Eturi S (2017). A study on blood urea and serum creatinine in diabetes mellitus from Sangareddy District, Telangana, India. International Journal of Medical and Health Research 3(12):132-136.

 
 

Uwaezuoke SN (2017). The role of novel biomarkers in predicting diabetic nephropathy: a review. International Journal of Nephrology and Renovascular Disease10:221-231.
Crossref

 
 

Wang S, Ma W, Yuan Z, Wang S, Yi X, Jia H, Xue F (2016). Association between obesity indices and type 2 diabetes mellitus among middle-aged and elderly people in Jinan, China: a cross-sectional study. BMJ Open 6(11):1-9.
Crossref

 
 

Xia J, Li L, Ren W, Zheng X, Liu C, Li J, Chen T, Li X, Wang L, Hu Y (2015). Correlation of increased plasma osteoprotegerin and cardiovascular risk factors in patients with adult growth hormone deficiency. International Journal of Clinical and Experimental Medicine 8(3):3184-3192.

 
 

Xin YL, Wang Y, Chi J, Zhu X, Zhao H, Zhao S, Wang Y (2019). Elevated free fatty acid level is associated with insulin-resistant state in nondiabetic Chinese people. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 12:139-147.
Crossref

 
 

Zanetti D, Bergman H, Burgess S, Assimes TL, Bahalla V, Ingelsson E (2020). Urinary Albumin, Sodium, and Potassium and Cardiovascular Outcomes in the UK Biobank: Observational and Mendelian Randomization Analyses. Hypertension 75(3):714-722.
Crossref

 
 

Zhu H, Liu M, Yu H, Liu X, Zhong Y, Shu J, Fu X, Cai G, Chen X, Geng W, Yang X, Wu M, Li Z, Zhang D (2017). Glycopatterns of Urinary Protein as New Potential Diagnosis Indicators for Diabetic Nephropathy. Journal of Diabetes Research 2017:1-14.
Crossref