October 2022

Prevalence and associated risk factors of Vitamin D deficiency in children under five years of age, at the Diamniadio Children's Hospital in Senegal

Vitamin D deficiency (VDD) is a public health problem which affects all human beings including dark-skinned subjects. In children, it can cause disabilities associated with skeletal abnormalities such as rickets or stunted growth. VDD is also associated with a significant risk of extra-skeletal, infectious, auto-immune, neoplastic, and cardiovascular diseases. The concentration of 25 (OH) D is currently considered as...

Author(s): Abou Ba, Najah Fatou Coly, Idrissa Basse, El Hadji Ibrahima Kane, Penda Awa Ka, Mamadou Soumboundou, , Souleymane Thiam, Abdourahmane Samba, Arame Ndiaye, Idrissa Yaya Soumah, Fatou Diedhiou, Fatou Cissé, Moustapha Djité, Néné Oumou Kesso Barry, Pape Matar Kandji, Papa Madiéye Gueye, Fatou Diallo Agne, Ndéye Ramatoulaye Diagne Gueye,

October 2022

Investigation into the intake of a popular polyherbal drug (Jalin Herbal Mannex Liquid) on selected biochemical indices of male wister rats

Jalin Herbal Mannex Liquid (JHML) is a polyherbal formulation from honey, Panax ginseng, Liriosma ovate, and Lepidium mehenil, intended for enhanced sexual performance and improve sperm count in men. JHML was studied via its effect on body weight, biochemical indices and histopathology of the testes. Twenty healthy Wistar rats of 120 -150 g weight were allotted into groups A and B., of ten rats each, group A (control),...

Author(s): Kpomah, E. D. and Arhoghro, E. M.

November 2022

Physicochemical parameters of Blighia sapida (K.D. Koenig) oil extracted in Togo

Oils extracted from Blighia sapida fruits are usually consumed without any information on its chemical composition. However the bad quality of oil can be a source of toxicity. Thus, the aim of this study is to investigate the physicochemical quality of the oil extracted from B. sapida from Togolese flora. To reach the goal of the study, mature and immature of B. sapida arils were used for oil extraction by the solvent...

Author(s): Aklesso Nabede, Haziz Sina, Tiatou Souho, Mamatchi Mélila, Farid T. Bade, Adolphe Adjanohoun, Batcha Ouadja, Lamine Baba-Moussa and Kou’santa Amouzou

November 2022

Effects of Quantitative Trait Loci (QTLs) of BCL11A and HBS1L-MYB genes on clinical-biological variability of sickle cell disease in a Senegalese pediatric population

High levels of hemoglobin F (HbF) could reduce the severity of sickle cell disease (SCD) by inhibiting hemoglobin S (HbS) polymerization. HbF expression is modulated by the Quantitative Trait Loci (QTLs) located on the HBS1L-MYB intergenic region (HMIP) (rs28384513) and intron 2 of the B-cell lymphoma/leukemia 11A (BCL11A) gene (rs4671393, rs1427407). To assess the impact of QTLs of HbF on clinical and biological...

Author(s): Tall Fatou G., Ndour El hadji M., Djité Moustapha, Barry Oumou K., Kandji Pape M., Gueye Papa M., Cissé Aynina and Sall Philoméne Lopez