African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Review

The role of SEF14 fimbriae in pathogenesis and enhancing the immunity of Salmonella enteritidis

Zhu, C. H.1, Hassan, H. Musa1, 3, Wu, S. L. 2 and Zhu, G. Q.1*
1College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China. 2College of Animal Science and Technology, Yangzhou 225009, China. 3Faculty of Veterinary Science, University of Nyala, 155 Nyala, Sudan.
Email: [email protected]

  •  Accepted: 28 April 2009
  •  Published: 31 May 2009

Abstract

Food safety is an important component of effective prevention and control strategy for Salmonella enteritidis infection. The control strategies have been implemented in poultry with ultimate aim to reduce S. enteritidis out breaks in human. SEF14 fimbriae are expressed on strains of serogroup D salmonella and contribute their survival in macrophages. SEF14 fimbriae are immunogenic in the S. enteritidisinfected chicken. SEF14 antibodies is protective in mice, IgA and IgG response were found in sera of immunized chicken with SEF14 antigen. In this review we concluded that the immunogenecity of SEF14 antigens in the infected birds may serve as component of an effective sub-cellular vaccine for poultry.

 

Key words: Salmonella entertidis, SEF14 fimbriae, pathogenicity.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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