African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Antimelanogenic and antioxidant activities of Bifidobacterium infantis

Huey-Chun Huang1, Shao-Hua Chiu2, Hui-Ju Ke2, Shu-wen Chiu2, Sze-Yun Wu2 and Tsong-Min Chang2*
1Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan, Republic of China. 2Department of Applied Cosmetology and Graduate Institute of Cosmetic Science, Hung Kuang University, Taichung, Taiwan, Republic of China.
Email: [email protected]

  •  Accepted: 15 June 2011
  •  Published: 30 September 2011

Abstract

The study was aimed at investigating the antimelanogenic and antioxidative effects ofBifidobacterium infantis culture filtrate. The efficacy of the bacterial culture filtrate wasevaluated spectrophotometrically. The results revealed that B. infantis culture filtrate effectively scavenge 2, 2-diphenyl-1-picryl-hydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) ABTS radicals, and show potent reducing power in a dose-dependent pattern. Additionally, the bacterial culture filtrate suppresses murine B16F10 tyrosinase activity and the amount of melanin in a dose-dependent manner. We conclude that the B. infantis culture filtrate may be applied in the formulations of skin care cosmetics.

 

Key words: Bifidobacterium infantis, tyrosinase, melanin, antioxidant.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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