Abstract

For effective management of typhoid, diagnosis of the disease must be done with speed and accuracy. Laboratory diagnosis of typhoid fever requires isolation and identification of Salmonella enterica serotype Typhi. In many areas where the disease is endemic, laboratory capability is limited. Recent advances in molecular immunology have led to the identification of sensitive and specific markers for typhoid fever and technology to manufacture practical and inexpensive kits for their rapid detection. But their limitation paves way to continue to search for the ideal rapid tests to diagnose acute typhoid fever.

Key words:  New advances, typhoid diagnosis, typhidot®, tubex®, fimbrial antigen.