African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Monitoring report on 341 cases of adverse reactions caused by antitumor drugs

Hong-jun Guo, Fang Ren, Dongya Zhang and Mei Ji*
Department of Gynecology and Obstetrics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 410052 China
Email: [email protected]

  •  Accepted: 30 March 2012
  •  Published: 30 April 2012

Abstract

This study aimed to summarize the main adverse reactions caused by antitumor drugs in China’s Henan Province and to provide reliable basis for strengthening drug administration in the future. This is a retrospective study conducted to analyze the monitoring of reports on 341 cases of adverse reactions caused by antitumor drugs collected from some AAA hospitals in Henan Province. Along with age increase and adverse drug reactions increase, the incidence of adverse reactions caused by cytarabine is the highest, infusion is the most prone to adverse reactions, and digestive system damage is the most common adverse reaction. Antitumor drugs have big toxic side effect on human body and cause many adverse reactions, and the supervision of clinical application of antitumor drugs must be strengthened.

 

Key words: Antitumor drug, adverse reaction, monitoring report, retrospective study.