African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Bioinformatics analysis of Agouti gene among different species

Shuling Yang, Xianglong Li*, Rongyan Zhou, Lanhui Li and Yuhong Ren  
College of Animal Science and Technology, Agricultural University of Hebei, Baoding 071000, Hebei, China
Email: [email protected]

  •  Accepted: 30 March 2012
  •  Published: 30 April 2012

Abstract

Abbreviation

Agouti gene plays an important role in the synthesis and distribution of coat color in domestic animals. In this report, a total of 71 Agouti gene sequences with the complete coding region (CDS) belonging to 15 species were analyzed. The result indicated that the averaged net genetic distance (Da) and the averaged nucleotide divergence (Dxy) were 0.2256 and 0.2145, respectively. Much more genetic diversity was existed in Peromyscus maniculatus and Lama pacos. The genetic relationship between mammalian and Danio rerio was closer than that between birds and Danio rerio. The predicted promoter region of chicken Agouti gene was from 2600 bp to 3000 bp upstream of start codon.

 

Key words: Agouti gene, genetic diversity, differentiation, chicken promoter prediction.