Abstract

Drug resistance is now a public health crisis and global problem. This study was performed to identify the antibiotic susceptibility of urinary tract infections (UTI) in Sanqar City of Kermanshah, Iran. Urine specimens of 891 ambulatory patients over 18 years of age with clinically suspected UTI were referred from Physicians' Office (MD) to the Sanqar Hospital (Kermanshah, Iran) for urine culture from September 1, 2011 to December 31, 2012. These samples were cultivated in agar-blood and McConkey agar. For culture positive samples, antibiogram test was done by disk diffusion method in Muller-Hinton agar plate. The relevant results were reported based on Clinical and Laboratory Standards Institute (CLSI) criteria. Of the 891 urine specimens, 379 cases were urinary culture positive (42.28%). The most common uropathogens were Escherichia coli (78.1%) and Klebsiella pneumoniae (15%). High susceptibility patterns to: ciprofloxacin (95.3%), amikacin (93.9%), nalidixic acid (92.2%), gentamicin (89.2%) and nitrofurantoin (83.8%) among the E. coli isolates identified were observed. Ciprofloxacin and nalidixic acid are the most suitable antibiotics for the empirical treatment used for ambulatory patients over 18 years of age with urinary tract infections in the geographical area of this study.

Key words: Antibiotic resistance, uropathogens, antibiogram, antimicrobial susceptibility.