African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Synergic bactericidal activity of novel antibiotic combinations against extreme drug resistant Pseudomonas aeruginosa and Acinetobacter baumannii

Elsayed Aboulmagd
  • Elsayed Aboulmagd
  • Department of Medical Microbiology, College of Medicine, King Faisal University, Kingdom of Saudi Arabia, Department of Microbiology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
  • Google Scholar
Abdulrahman A. Alsultan
  • Abdulrahman A. Alsultan
  • Department of Medical Microbiology, College of Medicine, King Faisal University, Kingdom of Saudi Arabia.
  • Google Scholar


  •  Received: 02 November 2013
  •  Accepted: 05 February 2014
  •  Published: 26 February 2014

References

Aboulmagd E, Alsultan AA, Al Mohammad HI, Al-Badry S, Hussein EM (2013). In vitro synergistic activity of amikacin combined with subinhibitory concentration of tigecycline against extended spectrum β-lactamase-producing Klebsiella pneumoniae. J. Microbiol. Antimicrob. 5(5):44-49.
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Al-Agamy MH, Shibl AM, Zaki SA, Tawfik AF (2011). Antimicrobial resistance pattern and prevalence of metallo-β-lactamases in Pseudomonas aeruginosa from Saudi Arabia. Afr. J. Microbiol. Res. 5(30):5528-5533.
 
Albur M, Noel A, Bowker K, MacGowan A (2012). Bactericidal activity of multiple combinations of tigecycline and colistin against NDM-1-producing Enterobacteriaceae. Antimicrob. Agents Chemother. 56(6):3441-3443.
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AlSultan AA, Evans BA, Elsayed EA, Al-Thawadi SI, Al-Taher AY, Amyes S, Al-Dughaym AM, Hamouda A (2013). High frequency of carbapenem-resistant Acinetobacter baumannii in patients with diabetes mellitus in Saudi Arabia. J. Med. Microbiol. 62:885-888.
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Breilh D, Texier-Maugein J, Allaouchiche B, Saux MC, Boselli E (2013). Carbapenems. J. Chemother. 25(1):1-17.
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Cai Y, Chai D, Wang R, Liang B, Bai N (2012). Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies. J. Antimicrob. Chemother. 67(7):1607-1615.
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Gould IM (2008). The epidemiology of antibiotic resistance. Int. J. Antimicrob. Agents 32(Suppl 1):S2-9.
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Lee CR, Cho IH, Jeong BC, Lee SH (2013). Strategies to minimize antibiotic resistance. Int. J. Environ. Res. Public Health 10(9):4274-305.
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Lee K, Youg D, Jeong SH, Chong Y (2011). Multidrug-resistant Acinetobacter spp: increasingly problematic nosocomial pathogens. Yonsei Med. J. 52(6):879-891.
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Lesho E, Yoon EJ, McGann P, Snesrud E, Kwak Y, Milillo M, et al (2013). Emergence of colistin-resistance in extremely drug-resistant Acinetobacter baumannii containing a novel pmrCAB operon during colistin therapy of wound infections. J. Infect. Dis. 208(7):1142-1151.
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Lim LM, Ly N, Anderson D, Yang JC, Macander L, Jarkowski A 3rd, Forrest A, Bulitta JB, Tsuji BT (2010). Resurgence of colistin: a review of resistance, toxicity, pharmacodynamics, and dosing. Pharmacotherapy 30(12):1279-1291.
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Lim TP, Tan TY, Lee W, Sasikala S, Tan TT, Hsu LY, Kwa AL (2011). In-vitro activity of polymyxin B, rifampicin, tigecycline alone and in combination against carbapenem-resistant Acinetobacter baumannii in Singapore. PLoS One 6(4):e18485.
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Livermore DM (2009). Has the era of untreatable infections arrived? J. Antimicrob. Chemother. 64(Suppl 1):29-36.
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Magiorakos AP, Srinivasan A, Carey RB, Carmeli Y, Falagas ME, Giske CG, et al (2012). Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin. Microbiol. Infect. 18:268-281.
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Mammina C, Bonura C, Di Bernardo F, Aleo A, Fasciana T, Sodano C, Saporito MA, Verde MS, Tetamo R, Palma DM (2012). Ongoing spread of colistin-resistant Klebsiella pneumoniae in different wards of an acute general hospital, Italy, June to December 2011. Euro Surveill. 17(33). pii:20248.
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Marchaim D, Chopra T, Pogue JM, Perez F, Hujer AM, Rudin S, et al (2011). Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan Detroit, Michigan. Antimicrob. Agents Chemother. 55(2):593-599.
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Memish ZA, Shibl AM, Kambal AM, Ohaly YA, Ishaq A, Livermore DM (2012). Antimicrobial resistance among non-fermenting Gram-negative bacteria in Saudi Arabia. J. Antimicrob. Chemother. 67(7):1701-1705.
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Papp-Wallace KM, Endimiani A, Taracila MA, Bonomo RA (2011). Carbapenems: past, present and future. Antimicrob. Agents Chemother. 55(11):4943-4960.
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Paterson DL, Doi Y (2007). A step closer to extreme drug resistance (XDR) in gram-negative bacilli. Clin. Infect. Dis. 45(9):1179-1181.
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Paterson DL, Lipman J (2007). Returning to the pre-antibiotic era in the critically ill: the XDR problem. Crit. Care Med. 35(7):1789-1791.
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Pillai SK, Moellering RC, Eliopoulos GM (2005). Antimicrobial combinations. In: Antibiotics in Laboratory Medicine, Ed. V. Lorian, 5th ed. Lippincott Williams & Wilkins. pp. 365-440.
 
Rahal JJ (2006). Novel antibiotic combinations against infections with almost completely resistant Pseudomonas aeruginosa and Acinetobacter species. Clin. Infect. Dis. 1(43 Suppl 2):S95-99.
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Rai J, Randhawa GK, Kaur M (2013). Recent advances in antibacterial drugs. Int. Appl. Basic Med. Res. 3(1):3-10.
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Slama TG (2008). Gram-negative antibiotic resistance: there is a price to pay. Critical Care 12(Suppl 4):S4.
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Urban C, Mariano N, Rahal JJ (2010). In vitro double and triple bactericidal activities of doripenem, polymyxin B, and rifampin against multidrug-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother. 54(6):2732-2734.
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