April 2019
Anti-quorum quenching activity of methyl gallate isolated from galls of Guiera senegalensis J. F. Gmel (Combretaceae)
Many pathogenic bacteria produce virulence factors controlled by a mechanism of regulation named quorum sensing (QS). Inhibition of bacterial QS system is a more recent therapeutic approach to counterbalance the emergence of multi-drug resistant bacteria. This study aimed to assess the abilities of methanol extract from Guiera senegalensis galls and its isolated compound methyl gallate to quench the quorum sensing...
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