African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 357

Full Length Research Paper

Convergent preparation of 2-phenylethanol

Alofoje Unuigboje* and Bright Emenike
Department of Chemistry, Federal University of Technology, Owerri, Imo State, Nigeria.
Email: [email protected]

  •  Received: 07 January 2010
  •  Accepted: 06 May 2011
  •  Published: 30 June 2011


The convergent synthesis of 2-phenylethanol was executed with bromination of benzene in the presence of pyridine to give bromobenzene which was reacted with magnesium metal to give phenylmagnesium bromide. Ethene was generated from ethanol and converted to 1,2-dibromoethane which in turn was reacted with the Grignard in an inverse manner to give 2-phenylbromoethane. Reaction of 2-phenylbromoethane and aqueous sodium hydroxide, in acetone as solvent, yielded 2-phenylethanol.
      Key words: 2-Phenylethanol, 1,2-dibromoethane, 2-phenylbromoethane