African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 368

Full Length Research Paper

Extraction, purification and nuclear magnetic resonance (NMR) assignment of garcinoic acid from Garcinia kola (bitter kola) fruit

B. Jones Orock
  • B. Jones Orock
  • Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland.
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J. Henry Blackwell
  • J. Henry Blackwell
  • Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland.
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Yannick Ortin
  • Yannick Ortin
  • Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland.
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Paul Evans
  • Paul Evans
  • Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Dublin 4, Ireland.
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  •  Received: 22 February 2018
  •  Accepted: 26 April 2018
  •  Published: 31 May 2018

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Mazzini F, Betti M, Netscher T, Galli F, Salvadori P (2009). Configuration of the vitamin E analogue garcinoic acid extracted from garcinia kola seeds. {[α]D = -4.2 (c = 0.37, MeOH)}. Chirality, 21(5):519-524.
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Rein C, Demel P, Outten RA, Netscher T, Breit B (2007). Reagent directing group controlled organic synthesis: Total synthesis of (R,R,R)-α-tocopherol. Angewandte Chemie International Edition, 46(45):8670-8673.
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Terashima K, Shimamura T, Tanabayashi M, Aqil M, Akinniyi JA, Niwa M (1997). Constituents of the seeds of garcinia kola: Two new antioxidants, garcinoic acid and garcinal. {[α]D = 0 (c = 0.15, CHCl3)}. Heterocycles, 45(8):1559-1566.
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Terashima K, Takaya Y, Niwa M (2002). Powerful antioxidant agents based on garcinoic acid from garcinia kola. Bioorganic and Medicinal Chemistry, 10(5):1619-1625.
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Zhao Y, Lee MJ, Cheung C, Ju JH, Chen YK, Liu B, Hu LQ, Yang CS (2010). Analysis of multiple metabolites of tocopherols and tocotrienols in mice and humans. Journal of Agricultural and Food Chemistry, 58(8):4844-4852.
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