African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Chemical composition and biological screening of essential oils from Pistacia integerrima

Abdur Rauf1*, Ghias Uddin1, Mohammad Arfan1 and Naveed Muhammad2
1Institute of Chemical Sciences, University of Peshawar, Peshawar -25120, KPK, Pakistan. 2Department of Pharmacy, University of Peshawar, Peshawar KPK, Pakistan.
Email: [email protected] or [email protected]

  •  Accepted: 10 May 2013
  •  Published: 29 May 2013

Abstract

The chemical composition and biological screening of the essential oils of the gall of Pistacia integerrima was performed. Volatile chemical constituents were obtained by hydrodistillation followed by liquid-liquid extraction. The oil was found rich in 1-Tepinen-4-ol (28.82%), p-meth-1-en-8-ol, (43.38%), n-Octyl acetate (19.91%), and beta-Farnesene (7.88%). The concentration of α-terpinolene, limonene and α-thujene were less than 1%. The essential oils at the tested concentration (10, 100 and 1000 μg/ml) showed moderate to maximum phytotoxic effect. The maximum effect was observed with 1000 μg/ml (80%) followed by 100 μg/ml (60%) and 10 μg/ml (50%). The tested oils exhibited promising antibacterial activities. The zone on inhibition against Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Straptodirimu, Bacillus stearothermophilus and Salmonella typhimurium was 16, 18, 26, 22, 18 and 20 mm, respectively. In case of antioxidant activity, the oils exhibited a concentration dependent free radical scavenging effect.

 

Key words: Pistacia integerrima, essential oil, gas chromatography-mass spectrometry (GC-MS), antibacterial, antioxidant and phytotoxic.