Abstract

In quality approach for the development of clinical research in Africa, the level of knowledge and practices of professionals influences the quality of the trial, the confidence of the sponsors in the performance of sites. We evaluated the management and dispensing of experimental drugs in Burkina Faso. From January to June 2018, we conducted a descriptive cross-sectional study with a sample of pharmacists and state pharmacy assistants. Proportions were used to calculate their knowledge levels on management and compliance with good dispensing practices in clinical trials. A total of 30/41 targeted professionals participated in the study. Only 26% said they had clinical trial training, 54% never participated in the conduct of a clinical trial. Less than half of the staff had knowledge of the pharmaceutical file. Staff knowledge on the correct prescription validation procedure varied between 60-76 and between 56-76.6% on good treatment delivery and advice. The level of knowledge of pharmacy professionals in trial drug management was average. The knowledge and practical experience of professionals is relatively low in the management of the investigational drug. Respect for good clinical practices which should add value to the quality and safety of trials must be improved. The major challenges are the continuous training of staff, the strengthening of the regulatory framework on good clinical practice in order to increase the competitiveness of hospitals in the conduct of clinical trials.

Key word: Pharmacy professional, experimental drug management.