African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2288

Full Length Research Paper

A report on the analysis of 365 cases of adverse reactions of Chinese patent drugs for heart cerebrovascular diseases

Bin Xiang, Yong Peng and Yu-Gang Jiang*
Department of Neurosurgery, Second Xiangya Hospital of Central South University, Changsha, Hunan Province 410011, China
Email: [email protected]

  •  Accepted: 05 July 2012
  •  Published: 29 May 2013

Abstract

This research aimed to analyze the factors of heart cerebrovascular drugs that can lead to adverse reactions (ADRs) and to promote rational clinical drug use. Reports on cases of heart cerebrovascular diseases were collected in our hospital in 2001 to 2010, and medication and the clinical manifestations of the adverse reactions were analyzed. The incidence of adverse reactions was related with age, gender, routes of administration, dosage forms and other factors. The adverse reactions of heart cerebrovascular drugs were mainly related to dosage forms, the injections were especially more likely to cause adverse reactions, and the clinical manifestations were diversified. It was therefore suggested that doctors and patients pay more attention to the adverse drug reactions in the whole medication process.

 

Key words: Heart cerebrovascular, Chinese patent drugs, adverse reactions.