African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2195

Full Length Research Paper

Effects of corn peptides on exercise tolerance, free radical metabolism in liver and serum glutamic-pyruvic transaminase activity of mice

Fusheng Miao1*, Wenqian Yu1, Yaoguang Wang1, Meijuan Wang2, Xiangyan Liu1and Fenglin Li3
1Physical Education College, Liaoning Normal University, Dalian 116029, P.R. China. 2Department of National Traditional Sports,Shandong Sport University, Rizhao 276826, P.R. China. 3Department of Bioengineering, Jilin Agricultural Science and Technology College, Jilin 132101, P. R. China.
Email: [email protected]

  •  Accepted: 21 March 2010
  •  Published: 30 April 2010


In order to carry out research on the effects of corn peptides on exercise tolerance, free radical metabolism in liver and serum Glutamic-pyruvic transaminase (GPT) activity of mice, sixty Kun-Ming male mice were randomly divided into two experimental groups, that is , Group I (20 mice) and Group II (40 mice). Group Iwas a quiet group in which the mice were not trained; Group II was a trained group in which the mice were trained. Either group was divided into control group and administered group. The control groups were administered with 1.5 ml distilled water by gavage every morning. The administered groups were administered with 1.50% corn peptides solution at the same dose for 28 days. The trained groups were trained to swim for 4 weeks and then were forced to swim without a load until being exhausted. The time of swimming to exhaustion and the Superoxide dismutase (SOD), Malondialdehyde (MDA) of liver and serum GPT were measured. The results indicated that corn peptides could significantly increase the body exercise tolerance, have a potent function of anti-lipid peroxidation injury and could reduce the body damage caused by endogenous free radicals produced in the movement. In addition, corn peptides had obvious protective effects on the body's liver cell membrane.


Key words: Corn peptide, exercise tolerance, free radicals, glutamic-pyruvic transaminase.