African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Anti-inflammatory activity of the venom from samsum ants Pachycondyla sennaarensis

M. A. Dkhil*, A. S. Abdel-Baki, S. Al-Quraishi and M. Al-Khalifa
Zoology Department, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia.
Email: [email protected]

  •  Accepted: 29 January 2010
  •  Published: 31 March 2010

Abstract

Black ants considered as heath hazard problem in many parts of the world. Sting of these ants caused local to systematic reactions and sometimes anaphylaxis. In this study, we proved that the black ant (samsum) venom exerts an anti-inflammatory action on mice model.  It was proven that the venom inhibited xylene induced ear swelling in mice with a percentage nearly equal to that of diclofenac. This result was supported by the histological studies which revealed that venom reduced the thickness of the inflamed ears and the cellular infiltration.

 

Key words: Samsum ant, venom, anti-inflammation, xylene induced ear swelling.