March 2010
Safety evaluation of aqueous extract of unripe berries of Solanum aculeastrum in male Wistar rats
The acute and sub-acute toxicity of aqueous extract of the fresh, unripe berries ofSolanum aculeastrum was investigated in male Wistar rats. In the acute toxicity study, toxicity symptoms such as hypoactivity, respiratory distress and epistaxis which disappeared 72 h post treatment, were observed in all the extract treated animals. Except for the 125 mg/kg body weight of the extract, all the other dose levels (250,...
March 2010
Management of superficial fungal infections with Senna alata (“alataâ€) soap: A preliminary report
The paper presents a preliminary report on the observational studies on Senna alata soap for the management of superficial skin infections among the inmates of Ilesa Prison, Nigeria. Thirty three inmates were recruited for the study and randomly distributed into 19 treatments and 14 controls. S. alata leaf powder was incorporated into the soap consisting of caustic soda (NaOH) and palm kernel oil...
March 2010
Effects of ethanol extract of Azadirachta indica leaves on some immunological and haematological parameters of diabetic Wistar rats
The effects of ethanol extract of Azadirachta indica (family: meliaceae) leaves on immunological and haematological parameters of alloxan-induced diabetic rats were investigated with a view to ascertaining its involvement in the immunological or inflammatory control of diabetic vascular complications. Total white blood cell, red blood cell, total lymphocyte and neutrophil counts were determined by...
March 2010
Drug adherence amongst tuberculosis patients in the University of Ilorin Teaching Hospital, Ilorin, Nigeria
Tuberculosis is a preventable, treatable and curable disease provided the precautionary measures and drug adherence are strictly adhered to. Structured questionnaires were administered to 280 tuberculosis patients diagnosed at the Pulmonary Unit of University of Ilorin Teaching Hospital, Ilorin; a tertiary healthcare centre in Nigeria. There were 166 males and 114 females giving male to female ratio of 1.4:1.0. There...
March 2010
Anti-inflammatory activity of the venom from samsum ants Pachycondyla sennaarensis
Black ants considered as heath hazard problem in many parts of the world. Sting of these ants caused local to systematic reactions and sometimes anaphylaxis. In this study, we proved that the black ant (samsum) venom exerts an anti-inflammatory action on mice model. It was proven that the venom inhibited xylene induced ear swelling in mice with a percentage nearly equal to that of diclofenac. This result was...
March 2010
Anti-inflammatory activity of the venom from samsum ants Pachycondyla sennaarensis
Black ants considered as heath hazard problem in many parts of the world. Sting of these ants caused local to systematic reactions and sometimes anaphylaxis. In this study, we proved that the black ant (samsum) venom exerts an anti-inflammatory action on mice model. It was proven that the venom inhibited xylene induced ear swelling in mice with a percentage nearly equal to that of diclofenac. This result was...
March 2010
Disease management by vaccination using Escherichia coli antigens
A major challenge for health care in 21st century is the increase in level of resistance to pathogens and effective vaccines to prevent the often life threatening infections are urgently required. Pathogen has been investigated for their potential use either as therapeutic or prophylactic vaccines, in order to identify new antigens of diagnostic and vaccine potential. The present investigation was done with five...
March 2010
Total phenolics and antioxidant activity of Tridax procumbens Linn.
Traditional medicinal plant, Tridax procumbens was analyzed for reducing power ability as an antioxidant using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and for total phenolics using the Folin-Ciocalteu method. The results of the analysis show that T. procumbens has a percentage antioxidant activity (AA %) of 96.70 which was observed to be higher than those of gallic (92.92%) and ascorbic acids...
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