African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2142

Table of Content: March 2010; 4(3)

March 2010

Safety evaluation of aqueous extract of unripe berries of Solanum aculeastrum in male Wistar rats

The acute and sub-acute toxicity of aqueous extract of the fresh, unripe berries ofSolanum aculeastrum was investigated in male Wistar rats. In the acute toxicity study, toxicity symptoms such as hypoactivity, respiratory distress and epistaxis which disappeared 72 h post treatment, were observed in all the extract treated animals. Except for the 125 mg/kg body weight of the extract, all the other dose levels (250,...

Author(s): O. M. Aboyade, M. T. Yakubu, D. S. Grierson and A. J. Afolayan

  • Article Number: 685901527188

March 2010

Management of superficial fungal infections with Senna alata (“alata”) soap: A preliminary report

The paper presents a preliminary report on the observational studies on Senna alata soap for the management of superficial skin infections among the inmates of Ilesa Prison, Nigeria. Thirty three inmates were recruited for the study and randomly distributed into 19 treatments and 14 controls. S. alata leaf powder was incorporated into the soap consisting of caustic soda (NaOH) and palm kernel oil...

Author(s): A. T. Oladele, B. A Dairo, A. A. Elujoba and A. O. Oyelami

  • Article Number: C99580B27230

March 2010

Effects of ethanol extract of Azadirachta indica leaves on some immunological and haematological parameters of diabetic Wistar rats

The effects of ethanol extract of Azadirachta indica (family: meliaceae) leaves on immunological and haematological parameters of alloxan-induced diabetic rats were investigated with a view to ascertaining its involvement in the immunological or inflammatory control of diabetic vascular complications. Total white blood cell, red blood cell, total lymphocyte and neutrophil counts were determined by...

Author(s): Itemobong S Ekaidem, Item J Atangwho, Henry D Akpan, Itoro F Usoh, Oboso E Etim and Patrick E Ebong

  • Article Number: E35246927633

March 2010

Drug adherence amongst tuberculosis patients in the University of Ilorin Teaching Hospital, Ilorin, Nigeria

Tuberculosis is a preventable, treatable and curable disease provided the precautionary measures and drug adherence are strictly adhered to. Structured questionnaires were administered to 280 tuberculosis patients diagnosed at the Pulmonary Unit of University of Ilorin Teaching Hospital, Ilorin; a tertiary healthcare centre in Nigeria. There were 166 males and 114 females giving male to female ratio of 1.4:1.0. There...

Author(s): S. I. Bello and O. A. Itiola

  • Article Number: 135DA2427696

March 2010

Anti-inflammatory activity of the venom from samsum ants Pachycondyla sennaarensis

Black ants considered as heath hazard problem in many parts of the world. Sting of these ants caused local to systematic reactions and sometimes anaphylaxis. In this study, we proved that the black ant (samsum) venom exerts an anti-inflammatory action on mice model.  It was proven that the venom inhibited xylene induced ear swelling in mice with a percentage nearly equal to that of diclofenac. This result was...

Author(s): M. A. Dkhil, A. S. Abdel-Baki, S. Al-Quraishi and M. Al-Khalifa

  • Article Number: 5C728A227736

March 2010

Anti-inflammatory activity of the venom from samsum ants Pachycondyla sennaarensis

Black ants considered as heath hazard problem in many parts of the world. Sting of these ants caused local to systematic reactions and sometimes anaphylaxis. In this study, we proved that the black ant (samsum) venom exerts an anti-inflammatory action on mice model.  It was proven that the venom inhibited xylene induced ear swelling in mice with a percentage nearly equal to that of diclofenac. This result was...

Author(s): M. A. Dkhil, A. S. Abdel-Baki, S. Al-Quraishi and M. Al-Khalifa

  • Article Number: 984B34727739

March 2010

Disease management by vaccination using Escherichia coli antigens

A major challenge for health care in 21st century is the increase in level of resistance to pathogens and effective vaccines to prevent the often life threatening infections are urgently required. Pathogen has been investigated for their potential use either as therapeutic or prophylactic vaccines, in order to identify new antigens of diagnostic and vaccine potential. The present investigation was done with five...

Author(s): P. Dhasarathan, S. Saravanan and A. Perianayagasamy

  • Article Number: 1BDB4A227774

March 2010

Total phenolics and antioxidant activity of Tridax procumbens Linn.

Traditional medicinal plant, Tridax procumbens was analyzed for reducing power ability as an antioxidant using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay and for total phenolics using the Folin-Ciocalteu method. The results of the analysis show that T. procumbens has a percentage antioxidant activity (AA %) of 96.70 which was observed to be higher than those of gallic (92.92%) and ascorbic acids...

Author(s): J. D. Habila, I. A. Bello, A. A. Dzikwi, H. Musa and N. Abubakar

  • Article Number: 02C73A727817