African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2191

Full Length Research Paper

Acupuncture effect on the magnetic resonance imaging (MRI) test for mild cognitive impairment leukoaraiosis

Xiaobin Hou1, Mingqi Wang2, Yunling Zhang3* and Jingwei Liu3
1Wangjing Hospital, Chinese China Academy of Chinese Medical Sciences, Beijing 100102, China. 2Beijing University of Chinese Medicine, Beijing, 100029, China. 3Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, 100078, China.
Email: [email protected]

  •  Accepted: 01 June 2012
  •  Published: 31 October 2012


Vascular cognitive impairment refers to the risk factors derived from blood vessels caused by a variety of levels and types of cognitive impairment, such as vascular mild cognitive impairment, vascular dementia and mixed dementia. Using acupuncture for mild cognitive impairment leukoaraiosis has impacts on the functional magnetic resonance. To know the neurotransmitter changes before and after acupuncture intervention in mild cognitive impairment with the functional magnetic resonance brain, laboratory for music and communication in infancy (LAMCI) cases (23), and 13 normal subjects (control group) cases were observed. Acupuncture treatment and the natural process group were observed for 3 months, respectively. Neuropsychological evaluation and magnetic resonance spectroscopy check were executed at the beginning and end of each day. Neuropsychological assessment includes mini-mental state examination (MMSE) and montreal cognitive assessment (MoCA), magnetic resonance imaging (MRI), spectroscopy N-acetylaspartate (NAA)/creatine (Cr), choline (Cho)/Cr, and myoinositol (MI)/Cr. The results showed that acupuncture can be used as an effective means of intervention for mild cognitive impairment leukoaraiosis, which can reduce activated brain regions in order to raise the efficiency of the task when stimulation is processed.


Key words: Acupuncture, leukoaraiosis, mild cognitive impairment, functional magnetic resonance, magnetic resonance spectroscopy.