African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Full Length Research Paper

Adherence to metabolic monitoring guidelines in atypical antipsychotic treated subjects: Do physicians comply?

Jesjeet Singh Gill1*, Tan Jin Teong1, Lee Hong Gee2, Tan Jing Wen2 and Rosy Jawan3
1Department of Psychological Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. 2Department of Pharmacy, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia. 3Department of Obstetrics and Gynecology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia.
Email: [email protected]

  •  Accepted: 04 October 2011
  •  Published: 08 January 2012

Abstract

Since the 1990s, the arrival of the new generation of antipsychotics, the atypical antipsychotics (AAP), heralded a new era in the management on psychotic patients as they are associated with much less side effects as the older drugs. However, the psychiatric community soon realized a new problem had emerged with these drugs, namely severe metabolic side effects. Several monitoring guidelines were soon published to guide treating physicians on how to deal with this issue. This study was aimed to assess adherence to the recommended guidelines by Malaysian doctors. Data concerning metabolic monitoring over 1 year were collected from 405 subjects newly started on AAP after June 2005, when the recommended guidelines were first implemented. Results showed that almost all the recommended tests/procedures were performed in less than 50% of patients during the recommended designated times. We recommend that the guidelines, which now serve only as a “guide”, be made a compulsory practice to safeguard the health of our patients.

 

Key words: Atypical antipsychotics, metabolic syndrome, monitoring guidelines.