African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2142

Table of Content: 8 January, 2012; 6(1)

January 2012

Pharmaceuticals in Sudan: Development in regulations, governance and implementation of national drug policies

The strategy of price liberalisation and privatisation had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and rules on the aforementioned strategy in particular to pharmacy regulations. Under the pressure of the new privatisation policy, the government introduced radical changes in the pharmacy regulations. The...

Author(s): Gamal K. M. Ali and Abdeen M. Omer

January 2012

Adherence to metabolic monitoring guidelines in atypical antipsychotic treated subjects: Do physicians comply?

Since the 1990s, the arrival of the new generation of antipsychotics, the atypical antipsychotics (AAP), heralded a new era in the management on psychotic patients as they are associated with much less side effects as the older drugs. However, the psychiatric community soon realized a new problem had emerged with these drugs, namely severe metabolic side effects. Several monitoring guidelines were soon published to...

Author(s): Jesjeet Singh Gill, Tan Jin Teong, Lee Hong Gee, Tan Jing Wen and Rosy Jawan

January 2012

Human blood glutathione (GSH) as a tool for arsenic detoxification

Arsenic is a major threat to a large part of the population due to its carcinogenic nature. The toxicity of arsenic emerges from glutathione (GSH) depletion caused by arsenic with unknown mechanism. GSH depletion leads to apoptosis, lipid peroxidation and eventual cell death. The present study was designed to provide insight into the extent of changes in GSH level by arsenic. Plasma and cytosolic fraction were...

Author(s): Naseem Ullah, Muhammad Farid Khan and Muhammad Mukhtiar

January 2012

Antinociceptive effect of Matricaria chamomilla on vincristine-induced peripheral neuropathy in mice

Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus, effective therapeutic strategy is required. In this study, the antinociceptive effect of Matricaria chamomilla (MC) hydroalcoholic extract and morphine on vincristine-induced peripheral neuropathy model in mice has been investigated. Experiments were performed on 60 Naval Medical Research Institute (NMRI) male mice. Mouse...

Author(s): Mir Hadi Khayate Nouri and Ali Namvaran Abbas Abad

January 2012

Activity of curcumin against human cytomegalovirus in vitro

Human cytomegalovirus (HCMV) is a main factor that causes many infective diseases, of which the drugs used for the treatment are limited. Our research revealed that curcumin could significantly inhibit HCMV in vitro. In the present study, high and middling dosage curcumin groups could significantly reduce HCMV DNA loads. Meanwhile, no significant differences were explored between ganciclovir (GCV) and high and...

Author(s): Ya-li LV#, An-jie LAN#, Yuan-yuan LAN, Chao LI, Ning LEI, Cheng WU and Li-hong LIU

January 2012

A meta-analysis of the efficacy and safety of arotinolol in the treatment of Chinese patients with essential hypertension

Arotinolol had been used for treatment of essential hypertension. We conducted a meta-analysis to compare the efficacy and safety of arotinolol with other antihypertensive drugs in treating essential hypertension. Medical databases and review articles were screened with prespecified criteria for randomized controlled trials that reported the effects of and adverse reactions to arotinolol and other antihypertensive drugs...

Author(s): Du Bing#,Cui Wen-peng#,Xu Guo-liang, Sun Guo-qiang, Wu Guo-dong, Qu Rui, Lin Shu-mei, Liu Yun-yang, Qin Ling

January 2012

Pharmacognostic studies of Viola betonicifolia

The pharmacognostic profile of crude drug has key role in standardization for quality, purity and drug identification. Various pharmacognostic studies of Viola betonicifolia were carried out in order to establish parameters for its identification and to check adulteration or contamination by other species of Viola. Morphological characteristic of the whole plant and its anatomic parts were studied by...

Author(s): Naveed Muhammad, Muhammad Saeed, Barkatullah, Muhammad Ibrar and Haroon Khan

January 2012

A meta analysis of the efficacy and safety of moxifloxacin in Chinese patients with multi-drug resistant pulmonary tuberculosisosis

This study was performed to evaluate the efficacy and safety of moxifloxacin in treating Chinese patients with multi-drug resistant pulmonary tuberculosisosis (MDR-TB). Medicinal databases and review articles were screened with pre-specified criteria for randomized controlled trials that reported the effects of and adverse reactions to moxifloxacin and other antituberculosisosis drugs in treating Chinese patients with...

Author(s): Shaoxia Liu, Shanshan Chen , Xinwei Ren and Guojun Zhang

January 2012

Effect of clinical pharmacist’s pharmaceutical care intervention to control hypertensive outpatients in China

Hypertension is an increasingly common health problem that affects more than 1 billion people throughout the world. Antihypertensive drugs are the current pharmacotherapy of choice, however uncontrolled blood pressure (BP) accounts for 7.1 million deaths worldwide each year. Little is known about the efficacy of clinical pharmacist’s pharmaceutical care on BP control and medication adherence. The aim of this study...

Author(s): Pei-Xi Zhao, Chao Wang, Li Qin, Ming Yuan, Qian Xiao, Ying-Hua Guo and Ai-Dong Wen

January 2012

Anabolic drugs consumption of high school students participating in school championships of physical education

This paper aims to analyse the use of anabolic drugs among Greek students participating in school championships of physical education (PE). In order to do it, a survey was conductedduring the 2008 to 2009 academic year in suburban, urban and metropolitan areas in Greece. The sample was 2,535 high school students from the 10 to 12th grade, participating in the school physical education...

Author(s): Konstantinos Goltsos, Dimitrios Soulas, Carlos A. Cordente Martínez, Maria Zakynthinaki, Antonio J. Monroy Antón and Gema Sáez Rodríguez