January 2012
Pharmaceuticals in Sudan: Development in regulations, governance and implementation of national drug policies
The strategy of price liberalisation and privatisation had been implemented in Sudan over the last decade, and has had a positive result on government deficit. The investment law approved recently has good statements and rules on the aforementioned strategy in particular to pharmacy regulations. Under the pressure of the new privatisation policy, the government introduced radical changes in the pharmacy regulations. The...
January 2012
Adherence to metabolic monitoring guidelines in atypical antipsychotic treated subjects: Do physicians comply?
Since the 1990s, the arrival of the new generation of antipsychotics, the atypical antipsychotics (AAP), heralded a new era in the management on psychotic patients as they are associated with much less side effects as the older drugs. However, the psychiatric community soon realized a new problem had emerged with these drugs, namely severe metabolic side effects. Several monitoring guidelines were soon published to...
January 2012
Human blood glutathione (GSH) as a tool for arsenic detoxification
Arsenic is a major threat to a large part of the population due to its carcinogenic nature. The toxicity of arsenic emerges from glutathione (GSH) depletion caused by arsenic with unknown mechanism. GSH depletion leads to apoptosis, lipid peroxidation and eventual cell death. The present study was designed to provide insight into the extent of changes in GSH level by arsenic. Plasma and cytosolic fraction were...
January 2012
Antinociceptive effect of Matricaria chamomilla on vincristine-induced peripheral neuropathy in mice
Vincristine-induced peripheral neuropathy is a major dose limiting side effect and thus, effective therapeutic strategy is required. In this study, the antinociceptive effect of Matricaria chamomilla (MC) hydroalcoholic extract and morphine on vincristine-induced peripheral neuropathy model in mice has been investigated. Experiments were performed on 60 Naval Medical Research Institute (NMRI) male mice. Mouse...
January 2012
Activity of curcumin against human cytomegalovirus in vitro
Human cytomegalovirus (HCMV) is a main factor that causes many infective diseases, of which the drugs used for the treatment are limited. Our research revealed that curcumin could significantly inhibit HCMV in vitro. In the present study, high and middling dosage curcumin groups could significantly reduce HCMV DNA loads. Meanwhile, no significant differences were explored between ganciclovir (GCV) and high and...
January 2012
A meta-analysis of the efficacy and safety of arotinolol in the treatment of Chinese patients with essential hypertension
Arotinolol had been used for treatment of essential hypertension. We conducted a meta-analysis to compare the efficacy and safety of arotinolol with other antihypertensive drugs in treating essential hypertension. Medical databases and review articles were screened with prespecified criteria for randomized controlled trials that reported the effects of and adverse reactions to arotinolol and other antihypertensive drugs...
January 2012
Pharmacognostic studies of Viola betonicifolia
The pharmacognostic profile of crude drug has key role in standardization for quality, purity and drug identification. Various pharmacognostic studies of Viola betonicifolia were carried out in order to establish parameters for its identification and to check adulteration or contamination by other species of Viola. Morphological characteristic of the whole plant and its anatomic parts were studied by...
January 2012
A meta analysis of the efficacy and safety of moxifloxacin in Chinese patients with multi-drug resistant pulmonary tuberculosisosis
This study was performed to evaluate the efficacy and safety of moxifloxacin in treating Chinese patients with multi-drug resistant pulmonary tuberculosisosis (MDR-TB). Medicinal databases and review articles were screened with pre-specified criteria for randomized controlled trials that reported the effects of and adverse reactions to moxifloxacin and other antituberculosisosis drugs in treating Chinese patients with...
January 2012
Effect of clinical pharmacist’s pharmaceutical care intervention to control hypertensive outpatients in China
Hypertension is an increasingly common health problem that affects more than 1 billion people throughout the world. Antihypertensive drugs are the current pharmacotherapy of choice, however uncontrolled blood pressure (BP) accounts for 7.1 million deaths worldwide each year. Little is known about the efficacy of clinical pharmacist’s pharmaceutical care on BP control and medication adherence. The aim of this study...
January 2012
Anabolic drugs consumption of high school students participating in school championships of physical education
This paper aims to analyse the use of anabolic drugs among Greek students participating in school championships of physical education (PE). In order to do it, a survey was conductedduring the 2008 to 2009 academic year in suburban, urban and metropolitan areas in Greece. The sample was 2,535 high school students from the 10 to 12th grade, participating in the school physical education...
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