African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2288

Full Length Research Paper

Assessment of herbal anthelmintics used by the farmers in Kirinyaga county, Kenya, for the treatment of helminthiosis in cattle

F. K. Njonge1*, M. Mutugi2, P. G. Kareru3, S. M. Githigia4, R. Waihenya2 and W. O. Nyakundi1    
1Department of Land Resources and Animal Sciences, Jomo Kenyatta University of Agriculture and Technology. P.O. Box 62,000-00200 Nairobi, Kenya. 2Department of Zoology, Jomo Kenyatta University of Agriculture and Technology. P.O. Box 62,000-00200 Nairobi, Kenya. 3Department of Chemistry, Jomo Kenyatta University of Agriculture and Technology. P.O. Box 62,000-00200 Nairobi, Kenya. 4College of Agricultural and Veterinary Sciences, University of Nairobi, P.O. Box 29053-00625, Nairobi, Kenya.    
Email: [email protected]

  •  Accepted: 30 April 2013
  •  Published: 08 August 2013

Abstract

The aim of this study was to assess and validate the herbal anthelmintic remedies used by farmers in Kirinyaga county, Kenya for the treatment of their cattle against gastrointestinal nematodes. The herbs used were identified via questionnaire surveys through focused group discussions. The aqueous extracts of plants used: Aspillia pluriseta, Vernonia lasiopus,Entada leptostachya and Erythrina abyssinica were prepared and using dosage between 10 and 30%, the viability of infective strongyle larvae were assessed for a period of 48 h. The results of the in vitro antihelmintic study indicated a high to moderate anthelmintic activity for the tested extracts. E. leptostachya exhibited the highest in vitro anthelmintic activity, while E. abyssinica had the lowest activity. The anthelmintic activity may have been due to the presence of saponins in the herbal remedies. There was a positive correlation between the saponin concentration and the anthelmintic activity of the extracts. In general, the in vitroanthelmintic activity increased with the extract concentration for the medicinal plants examined.

 

Key words: Anthelmintics, in-vitro, Entada leptostachya, dosage, husbandry.

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