African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2162

Full Length Research Paper

Evaluation of neuro-pharmacological activities in six homeopathic drugs

Farah-Saeed*
  • Farah-Saeed*
  • Department of Pharmacognosy, Dow College of Pharmacy, Dow University of Health Sciences, Karachi-Pakistan.
  • Google Scholar
Noor-Jahan
  • Noor-Jahan
  • Department of Pharmacology, Dow College of Pharmacy, Dow University of Health Sciences, Karachi-Pakistan.
  • Google Scholar
Mehjabeen
  • Mehjabeen
  • Department of Pharmacology, Faculty of Pharmacy, Federal Urdu University of Arts Science and Technology, Karachi-Pakistan.
  • Google Scholar
Mansoor Ahmad
  • Mansoor Ahmad
  • Research Institute of Pharmaceutical Sciences, University of Karachi-Pakistan.
  • Google Scholar


  •  Received: 28 February 2015
  •  Accepted: 16 March 2015
  •  Published: 22 March 2015

Abstract

The effects of extracts of Digitalis purpurea L., Sambucus nigra L., Thuja occidentalis L., Urtica urens L., Arctostaphylos uva-ursi L. and Apis mellifica L. were analyzed in vivo in mice. The analysis of neuro-pharmacologiacl activity was recorded at different doses such as 100, 300 and 500 mg/kg and compared with control and standard drug, Diazepam. The tested extracts exhibited significant neuro-pharmacological activities in open field, dip cage, light and dark, cage cross and forced swimming activities. Our research supports the safe and effective use of the extracts in low doses.

Key words: Neuro-pharmacological, open field activity, dip cage activity, light and dark activity, cage cross activity, forced swimming test.