African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2142

Table of Content: 22 March, 2015; 9(11)

March 2015

Evaluation of the antioxidant activity, antimicrobial effect and acute toxicity from leaves of Allophylus edulis (A. St.-Hil., A. Juss. Cambess &.) Hieron. ex Niederl

Allophylus edulis is a Brazilian plant  commonly used in the mid-west region of Brazil for treatment of disorders  related to oxidative stress such as diabetes, inflammation, hypertension and digestive diseases. The aims of the present study were to quantify flavonoids and phenolic compounds, evaluate the antioxidant activity, antimicrobial effect and acute toxicity of leaves of A. edulis. Ethanolic (EEAE) and...

Author(s): Cleide Adriane Signor Tirloni, Luis Fernando Benites Macorini, Uilson Pereira dos Santos, Paola dos Santos da Rocha, Salete Verônica Barros, Adriana Mary Mestriner Felipe de Melo, Maria do Carmo Vieira, Kely de Picoli Souza, and Edson Lucas dos Santos,

March 2015

In vivo hypoglycemic and alloxan induced antidiabetic activity of Xeromphis uliginosa Retz

Xeromphis uliginosa Retz. is an indigenous plant of Bangladesh. Traditionally this plant is used to treat many diseases. In order to explore the medicinal quality of this plant systematically, the crude methanol extract of roots was screened for antidiabetic activity in rats model. The antidiabetic action was determined by using oral glucose tolerance test (OGTT) and alloxan induced antidiabetic test. In OGTT, both...

Author(s): Mohammad Firoz Khan, Zahirul Islam Khan, Md. Rakib Uddin, Mohammad S. Rahman and Mohammad A. Rashid

March 2015

Evaluation of neuro-pharmacological activities in six homeopathic drugs

The effects of extracts of Digitalis purpurea L., Sambucus nigra L., Thuja occidentalis L., Urtica urens L., Arctostaphylos uva-ursi L. and Apis mellifica L. were analyzed in vivo in mice. The analysis of neuro-pharmacologiacl activity was recorded at different doses such as 100, 300 and 500 mg/kg and compared with control and standard drug, Diazepam. The tested extracts exhibited significant neuro-pharmacological...

Author(s): Farah-Saeed, Noor-Jahan, Mehjabeen and Mansoor Ahmad

March 2015

Effects of Jatropha gossypiifolia L. on the blood pressure and vascular reactivity of rats

This work investigated the effects of the ethanolic extract (EEJg) of aerial parts of Jatropha gossypiifolia L. and its aqueous (AFJg) and chloroformic (CFJg) fractions on the blood pressure and vascular reactivity (VR) in normotensive Wistar rats (NWR) and spontaneously hypertensive rats (SHR). In anaesthetized NWR, the EEJg and its fractions reduced mean blood pressure (MAP). The oral administration of EEJg (100...

Author(s): Selma do Nascimento Silva, Iracelle Carvalho Abreu, Maria do Socorro de Sousa Cartágenes, Maísa Carvalho Rezende, Karla Frida Torres Flister, Cristiane Tavares Machado, Roberto Sigfrido Gallegos Olea, Sônia Maria de Farias Freire, Marilene Oliveira da R. Borges and  Antônio Carlos Romão Borges

March 2015

Study on drug utilization pattern of antihypertensive medications on out-patients and inpatients in a tertiary care teaching hospital: A cross sectional Study

This study aimed to evaluate drug utilization of anti-hypertensive medications in a tertiary care teaching hospital. In this study, a cross sectional study was conducted in hypertensive who visited General Medicine department in a tertiary care teaching hospital, during the period of August, 2013 to August, 2014. 1407 new prescriptions were analyzed according IP/OP numbers of rational drug utilization by using WHO Core...

Author(s): Jainaf Nachiya, R. A. M., Parimalakrishnan, S. and Ramakrishna Rao, M.