African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2284

Full Length Research Paper

Hypoglycemic, hypolipidemic and kidney protective potential of combined formulation of Tribulus terrestris and Andrographis paniculata in alloxan induced mice

Istiak A.
  • Istiak A.
  • Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
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Hazra P.
  • Hazra P.
  • Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
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Das S. R.
  • Das S. R.
  • Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
  • Google Scholar
Hossain M. I.
  • Hossain M. I.
  • Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
  • Google Scholar
Aminatu A. S.
  • Aminatu A. S.
  • Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
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Rafiq K.
  • Rafiq K.
  • Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
  • Google Scholar


  •  Received: 04 May 2018
  •  Accepted: 05 June 2018
  •  Published: 08 July 2018

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Amin A, Lotfy M, Shafiullah M, Adeghate E (2006) The protective effect of Tribulus terrestris in diabetes. Annals of the New York Academy of Sciences 1084:391 401.
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El-Tantawy WH, Hassanin LA (2007) Hypoglycemic and hyperlipidemic effect of Tribulus alatusin steptozotocin-induced diabetic rats: A comparative study with T. terrestris (Caltrop). Indian Journal of Experimental Biology 45(9):785-90.

 

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Lakshmia V, Shishir S, Ashok KK, Abbas AM, Santosh KA (2014). Lipid Lowering potential of Andrographis paniculata (Nees).The Journal of Phytopharmacology 3(2):124-129.

 

Liu R, Liu IY, Bi X, Thompson RF, Doctrow SR, Malfroy B, Baudry M (2003). Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics. Proceedings of the National Academy of Sciences 100(14):8526-8531.
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Mutalik S, Sulochana B, Chetana M, Udupa N, Devi UP (2003). Preliminary studies on acute and subacute toxicity of an antidiabetic herbal preparation, dianex. Indian Journal of Experimental Biology 41(4):316-320.

 

Nugroho AE Rais IR, Setiawan I, Pratiwi PY, Hadibarata T, Tegar M, Pramono S (2014). Pancreatic effect of andrographolide isolated from Andrographis paniculata (Burm. f.) Nees. Pakistan Journal of Biological Sciences: PJBS 17(1):22-31.
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Premanath R, Nanjaiah L (2015). Antidiabetic and Antioxidant potential of Andrographis paniculata Nees leaf ethanol extract in streptozotocin induced diabetic rats.

 

Sen S, Chakraborty R, De B, Mazumder J (2011) Synergistic Activity of Tribulus Terrestris and Annona squamosa Extracts Against Alloxan Induced Diabetes And Hyperlipidemia In Rats. Pharma Science Monitor 2(2):0976-7908.

 

Sharifzadeh M, Ranjbar A, Hosseini A, Khanavi M (2017) The Effect of Green Tea Extract on Oxidative Stress and Spatial Learning in Streptozotocin-diabetic Rats. Iranian Journal of Pharmaceutical Research: IJPR 16(1):201-209.

 

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Wibudi A, Kiranadi B, Manalu W, winarto A, Suyono S (2008). The traditional plant, Andrographis paniculata (Sambiloto), exhibits insulin-releasing actions in vitro. Acta Medica Indonesiana 40(2):63-8.

 

Xie JT, Wang A, Mehendale S, Wu J, Aung HH, Dey L, Qiu S, Yuan CS (2003). Anti-diabetic effects of Gymnema yunnanense extract. Pharmacological Research 47(4):323-329.
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