African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2288

Full Length Research Paper

Hepatoprotective and free radical scavenging activities of methanol extract fractions of Capparis decidua Edgew (Forssk.) (Capparidaceae)

Mohamed Mirghani
  • Mohamed Mirghani
  • Department of Pharmacognosy, Faculty of Pharmacy, International University of Africa, Sudan.
  • Google Scholar
Hassan S. Khalid
  • Hassan S. Khalid
  • Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan.
  • Google Scholar
Mona S. Mohammed
  • Mona S. Mohammed
  • Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan.
  • Google Scholar
Ahmed Babiker Mohamed
  • Ahmed Babiker Mohamed
  • Department of Pharmacology, Faculty of Pharmacy, International University of Africa, Sudan.
  • Google Scholar
Amna Ali
  • Amna Ali
  • Department of Medical Biochemistry, Medicinal and Aromatic Plants Research Institute and Traditional Medicine, National Center for Research, P.O. Box, 2402, Khartoum, Sudan.
  • Google Scholar
Wadah Osman
  • Wadah Osman
  • Department of Pharmacognosy, Faculty of Pharmacy, University of Khartoum, Sudan.
  • Google Scholar
Waleed A Alobaid
  • Waleed A Alobaid
  • Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
  • Google Scholar
Ramzi A. Mothana
  • Ramzi A. Mothana
  • Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
  • Google Scholar


  •  Received: 21 July 2020
  •  Accepted: 12 August 2020
  •  Published: 30 September 2020

References

Aghel N, Rashidi I, Mombeini A (2007). Hepatoprotective activity of Capparis spinosa root bark against CCl4 induced hepatic damage in mice. Iranian Journal of Pharmaceutical Research 6(4):285-290.

 

Ali SA, Gameel AA, Mohamed AH, Al-Amin TH (2009). Hepatoprotective activity of aqueous and methanolic extracts of Capparis decidua stems against carbon tetrachloride induced liver damage in rats. Journal of Pharmacology and Toxicology 4(4):167-172.
Crossref

 

Asrani SK, Devarbhavi H, Eaton J, Kamath PS (2019). Burden of liver diseases in the world. Journal of Hepatology 70(1):151-171.
Crossref

 

Chahlia N (2009). Evaluation of hypolipidaemic activity of Capparis decidua. International Journal of Biomedical Science 5(1):70-73.

 

Dev SK, Shukla A, Choudhury PK, Singh GK (2015). Analgesic and anti-nociceptive activity of hydroethanolic extract of Capparis decidua Linn. Asian Journal of Pharmacy and Pharmacology 1(1):40-44.

 

Dhakad PK, Sharma PK, Kumar S (2016). A review on ethnobiological and medicinal potential of Capparaceae family plant: Capparis decidua (Forssk.) Edgew. Advances in.Pharmacology and Pharmacy 4(3):27-39.

 

Fabricant DS, Fransworth NR (2001). The value of plants used in traditional medicine for drug discovery. Environmental Health Perspectives 109(1):69-75.
Crossref

 

Farag M, Mohammed MS, Foud I, Wadah JA Mohamed MS (2015). The role of natural products in drug discovery and development. World Journal of Pharmaceutical Research 4(3):22-33.

 

Gupta M, Mazunder U, Kumar T, Gomathi P, Kumar R (2004). Antioxidant and hepatoprotective effects of Buhinia racemosa against paracetamol and carbon tetrachloride induced liver damage in rats. Iranian Journal of Pharmacology and Therapeutics 3(1):12-20.

 

Haq MZ, Cayar S, Qayum M, Imran I, Feo VD (2011). Compositional studies: antioxidant and anti-diabetic activities of Capparis decidua (Forssk.) Edgew. International Journal of Molecular Sciences 12(12):8846-8861.
Crossref

 

Mohammed MS, Khalid HS, Muddathir AK, Siddiqui NA, Ali M (2012). A Novel germacranolide sesquiterpene lactone with anti-inflammatory effect from Capparis decidua (Forsk.). International Journal of Research in Pharmacy and Chemistry 2(4):1073-1077.

 

Mohammed MS, Khalid HS, Muddathir AK, Tahir KEH, Osman B, Osman WJA, Basudan O (2014). Effect of two sesquiterpene lactones from Capparis decidua (Forsk.) on arachidonic acid and adenosine diphosphate-induced platelets aggregation. Journal of Phytopharmacology 3(3):176-179.

 

Nazar S, Hussain MA, Khan A, Muhammad G, Tahir MN (2020). Capparis decidua Edgew (Forssk.): A comprehensive review of its traditional uses, phytochemistry, pharmacology and nutrapharmaceutical potential. Arabian Journal of Chemistry 13(1):1901-1916.
Crossref

 

Pattanayak SP, Priyashree S (2008). Hepatoprotective activity of the leaf extracts from Dendrophthoe falcate (L.F) Ettingsh against carbon tetrachloride- induced toxicity in Wistar albino rats. Pharmacognosy Magazine 4(15):218-222.

 

Purohit A, Vyas KB (2006). Anti-atherosclerotic effect of Capparis decidua fruit extract in cholesterol-fed rabbits. Pharmaceutical Biology 44(3):172-177.
Crossref

 

Rathee P, Rathee D, Rathee D, Rathee S (2012). In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines. Natural Product Research 26(18):1737-1740.
Crossref

 

Rathee S, Mogla OP, Sardana S, Vats M, Rathee P (2010). Anti-diabetic activity of Capparis decidua Forsk Edgew. Journal of Pharmacy Research 3(2):231-234.

 

Satyanarayana T, Mathews AA, Vijetha P (2008). Phytochemical and pharmacological review of some Indian Capparis species. Pharmacognosy Reviews 2(4):36-45.

 

Sharma B, Kumar P (2008). Extraction and pharmacological evaluation of some extracts of Tridax procumbens and Capparis decidua. International Journal of Applied Research in Natural Products 1(4):5-12.

 

Shimada K, Fujikawa K, Yahara K, Nakamura T (1992). Antioxidative properties of xanthan on the antioxidation of soybean oil in cyclodextrin emulsion. Journal of Agricultural and Food Chemistry 40(6):945-948.
Crossref

 

Singh P, Mishra G, Srivastava S, Jha KK, Khosa RL (2011). Traditional uses, phytochemistry and pharmacological properties of Capparis decidua: an overview. Der Pharmacia Lettre 3(2):71-82.

 

Upadhyay RK, Ahmad S, Tripathi R, Rohtagi L, Jain SC (2010). Screening of antimicrobial potential of extracts and pure compounds isolated from Capparis decidua. Journal of Medicinal Plants Research 4(6):439-445.

 

Yadav RNS, Agarwala M (2011). Phytochemical analysis of some medicinal plants. Journal of Phytology 3(12):10-14.