African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2284

Full Length Research Paper

Evaluation of hypoglycemic activity and safety of Carica papaya seed extracts in alloxan-induced diabetic mice

Samuel P. Kagame
  • Samuel P. Kagame
  • Kenya Medical Research Institute, Center for Traditional Medicine and Drugs Research, P. O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar
Nicholas Mwikwabe
  • Nicholas Mwikwabe
  • Kenya Medical Research Institute, Center for Traditional Medicine and Drugs Research, P. O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar
Peter Mwitari
  • Peter Mwitari
  • Kenya Medical Research Institute, Center for Traditional Medicine and Drugs Research, P. O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar
Moses Gichua
  • Moses Gichua
  • Jomo Kenyatta University of Agriculture and Technology P. O. Box GPO 62000 Nairobi, Kenya.
  • Google Scholar


  •  Received: 23 January 2018
  •  Accepted: 26 February 2018
  •  Published: 31 October 2019

References

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Aravind G, Debijit B, Duraivel S, Harish G (2013): Traditional and medicinal uses of Carica papaya. Journal of Medicinal Plants Studies 1(1):7-15

 
 

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Chege MP (2010). Risk\ factors for type 2 diabetes mellitus among patients attending a rural Kenyan hospital. African Journal of Primary Health Care and Family Medicine 2(1):5.
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Chinoy NJ, Padman P (1996). Anti-infertility investigation on the benzene extract of Carica papaya seeds in male and female albino rats. Journal Aromatic Plant Science 18(3):489-494.

 
 

Chinoy NJ, Trivedi D, Joshi H (1995). Effect of Carica papaya seed extract on female rat ovaries and uteri. Phytotherapy Research 9(3)169-175.
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Goycheva P, Gadjeva V,Popov B (2006).Mini-review Oxidative Stress And Its Complications In Diabetes. Trakia Journal of Sciences 4(1):1-8.

 
 

Harborne A (1998). Phytochemical methods a guide to modern techniques of plant analysis: springer science and business media.

 
 

International Diabetes Federation (IDF) (2011). Diabetes Atlas, 5th Edition. 

 
 

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Parle M, Gurdita (2011). Basketful Benefits of Papaya: international research journal of pharmacy 2(7):6-12.

 
 

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Sidi-Aliyu B (2006).Common Ethnomedicinal Plants of the Semiarid Regions of West Africa: Their Description and Phytochemicals (Vol. 1): Triumph publishing company.

 
 

Yang L, Colditz GA (2015). Prevalence of overweight and obesity in the United States, 2007-2012. JAMA internal medicine 175(8):1412-1413.
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Xu Z, Wang X, Zhou M, Ma L, Deng Y, Zhang H, Zhao A, Zhang Y, Jia W (2008). The antidiabetic activity of total lignan from Fructus Arctii against alloxan-induced diabetes in mice and rats. Phytotherapy Research 22:97-101.
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