African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2286

Full Length Research Paper

Jatropha dioica, an Aztec plant with promising pharmacological properties: A systematic review

Agustina Ramírez-Moreno
  • Agustina Ramírez-Moreno
  • Faculty of Biological Sciences, Autonomous University of Coahuila, Carr. Torreón-Matamoros, km 7.5, CP.27276. Torreón, Coahuila, Mexico.
  • Google Scholar
Dealmy Delgadillo-Guzmán
  • Dealmy Delgadillo-Guzmán
  • Department of Pharmacology, Faculty of Medicine, Torreon Unit, Autonomous University of Coahuila, Torreón, Coahuila, Mexico.
  • Google Scholar
Verónica Bautista-Robles
  • Verónica Bautista-Robles
  • Food and Nutrition, Faculty of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brasil.
  • Google Scholar
Jolanta E Marszalek
  • Jolanta E Marszalek
  • Faculty of Biological Sciences, Autonomous University of Coahuila, Carr. Torreón-Matamoros, km 7.5, CP.27276. Torreón, Coahuila, Mexico.
  • Google Scholar
Hady Keita
  • Hady Keita
  • Division of Postgraduate Studies, University of Sierra Sur, Miahuatlán de Porfirio Díaz, Oaxaca, CP. 70805, Mexico.
  • Google Scholar
Ansoumane Kourouma
  • Ansoumane Kourouma
  • Department of Pharmaceutical Sciences, Gamal Abdel Nasser University of Conakry, Republic of Guinea.
  • Google Scholar
Sergio Alberto Ramírez García
  • Sergio Alberto Ramírez García
  • Division of Postgraduate Studies, University of Sierra Sur, Miahuatlán de Porfirio Díaz, Oaxaca, CP. 70805, Mexico.
  • Google Scholar
Jesús Rafael Rodríguez Amado
  • Jesús Rafael Rodríguez Amado
  • Food and Nutrition, Faculty of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brasil.
  • Google Scholar
José Carlos Tavares-Carvalho
  • José Carlos Tavares-Carvalho
  • Drug Research Laboratory, Federal University of Amapá, Rodovia Juscelino Kubitschek, km 2, Jardim Marco Zero, CEP: 68903-419 Macapá, AP, Brazil.
  • Google Scholar


  •  Received: 01 April 2020
  •  Accepted: 10 June 2020
  •  Published: 31 July 2020

References

Aggie H (2010). Leatherstem, Sangra de Drago, Sangregrado, Sangre de Grado, Tecote Prieto, Tocote Prieto, Telondillo, Tlapalezpatli, Pinon del Cerro, Coatli, Torte Amarillo, Drago Jatropha dioica Euphorbiaceae. 
 
Aguilera-Carbo AF, Augur C, Prado-Barragan LA, Aguilar CN, Favela-Torres E (2008). Extraction and analysis of ellagic acid from novel complex sources. Chemical Papers 62(4):440-444.
Crossref
 
Aladodo RA, Muhammad NO, Balogun EA (2013). Effects of Aqueous Root Extract of Jatropha curcas on Hyperglycaemic and Haematological Indices in Alloxan-induced. Fountain Journal of Natural and Applied Sciences 2(1):52-58.
 
Alarcon-Aguilara FJ, Roman-Ramos R, Perez-Gutierrez S, Aguilar-Contreras A, Contreras-Weber CC, Flores-Saenz JL (1998). Study of the anti-hyperglycemic effect of plants used as antidiabetics. Journal of Ethnopharmacology 61(2):101-110. 
Crossref
 
Alanís-Garza BA, González-González GM, Salazar-Aranda R, Waksman de Torres N, Rivas-Galindo VM (2007). Screening of antifungal activity of plants from the northeast of Mexico. Journal of Ethnopharmacology 114(3):468-471. 
Crossref
 
Araujo-Espino DI, Zamora-Pérez AL, Zúñiga-González GM, Gutiérrez-Hernández R, Morales-Velázquez G, Lazalde-Ramos BP (2017). Genotoxic and cytotoxic evaluation of Jatropha dioica Sessé ex Cerv. by the micronucleus test in mouse peripheral blood. Regulatory Toxicology and Pharmacology 86:260-264. 
Crossref
 
Arturo AV, Asseleih LMC, María Elena, R (1994). Atlas de las plantas medicinales de la medicina tradicional mexicana. (B. de la medicina tradicional mexicana, Ed.) (1st ed.). México, D.F.
 
Ascacio-Valdés JA, Aguilera-Carbó A, Rodríguez-Herrera R, Aguilar-González C, Alberto J, Valdés A (2013). Determination of ellagic acid in native plants from the Mexican semi-desert. Revista Mexicana de Ciencias Farmacéuticas 44(2).
 
Barba Avila MD, Croce Hernandez M, Cerda Lemus M (2003). Plantas Útiles de la región semiárida de Aguascalientes (U. A. de Aguascalientes, Ed.) (1ra ed.). México.
 

Baquero LCP, Gordillo JV (2013). Actividad antioxidante y antibacteriana de extractos de hojas de cuatro especies agroforestales de la Orinoquía colombiana. Revista Cubana de Plantas Medicinales 18(1):57-70.

View

 
Baskar AA, Ignacimuthu S, Paulraj GM, Al Numair KS (2010). Chemopreventive potential of β-Sitosterol in experimental colon cancer model - An In vitro and In vivo study. BMC Complementary and Alternative Medicine 10(24):1-10. 
Crossref
 

Bravo Luna L, Bermúdez Torres K, Montes Belmont R (2000). Inhibición de Fusarium moniliforme mediante polvos vegetales y algunos de sus componentes químicos. 

View

 
Burgueño-Tapia E, Chávez-Castellanos K, Cedillo-Portugal E, Joseph-Nathan P (2017). Absolute configuration of diterpenoids from Jatropha dioica by vibrational circular dichroism. Tetrahedron Asymmetry 28(1):166-174. 
Crossref
 
Can-Aké R, Erosa-Rejón G, May-Pat F, Peña-Rodríguez LM, Peraza-Sánchez SR (2004). Bioactive terpenoids from roots and leaves of Jatropha gaumeri. Revista de La Sociedad Química de México 48(1):11-14.
 
Castillo F, Hernández D, Gallegos G, Mendez M, Rodríguez R, Reyes A, Aguilar CN (2010). In vitro antifungal activity of plant extracts obtained with alternative organic solvents against Rhizoctonia solani Kühn. Industrial Crops and Products 32(3):324-328. 
Crossref
 
Chandran R, Primelazhagan T, Shanmugam S, Thankarajan S (2016). Antidiabetic activity of Syzygium calophyllifolium in Streptozotocin-Nicotinamide induced Type-2 diabetic rats. Biomedicine and Pharmacotherapy 82:547-554. 
Crossref
 
Chen Z, Cai Y, Phillipson D (1994). Studies on the Anti-Tumour, Anti-Bacterial, and Wound- Healing Properties of Dragon's Blood. Planta Medica 60:541-545.
Crossref
 
Cirilo Aguilar B, Cantú Martínez P, Verde Star M, Mata Cárdenas B (2011). Uso de la Herbolaria en el Cuidado de la Salud. Revista de Salud Pública y Nutrición 12(2):1-6.
Crossref
 
Civelek M, Flory S, Meloh H, Fitzenberger E, Wenzel U (2019). The polyphenol quercetin protects from glucotoxicity depending on the aggresome in Caenorhabditis elegans. European Journal of Nutrition 1-7. 
Crossref
 
Dominguez GC, Franco R, Villareal A (1980). Riolozatrione, a new class diterpene from Jatropha dioica var. sesseliflora (roots). Retrieved February 17, 2018
Crossref
 
Eggli U (Ed.). (2001). Illustrated Handbook of Succulent Plants: Monocotyledons (1st ed.). Springer-Verlag Berlin Heidelberg. 
Crossref
 
Escareño-Piña E (2017). Acción antimicrobiana de extractos de Jatropha dioica Cerv. Unidad Acad Ondon 57-63.
 
Flores-Torres A, Montaña C, Franco M (2019). Coexistence and the niche in a nurse-cactus interaction: Is cyclic dynamics justified? Journal of Ecology 107(1):407-417. 
Crossref
 
Fresnedo-Ramírez J, Orozco-Ramírez Q (2013).Diversity and distribution of genus Jatropha in Mexico. Genetic Resources and Crop Evolution 60(3):1087-1104. 
Crossref
 
Galleano M, Pechanova OG, Fraga C (2010). Hypertension, Nitric Oxide, Oxidants, and Dietary Plant Polyphenols. Current Pharmaceutical Biotechnology 11(8):837-848. 
Crossref
 
Gamiotea-Turro D, Camaforte NAP, Valerino-Diaz AB, Ortiz Nuñez Y, Rinaldo D, Dokkedal AL (2018). Qualitative and Quantitative Analysis of Ethanolic Extract and Phenolic Fraction of Jatropha aethiopica (Euphorbiaceae) Leaves and Their Hypoglycemic Potential. Journal of Agricultural and Food Chemistry 66(6):1419-1427. 
Crossref
 
González RC, González-Chávez MCA (2006). Metal accumulation in wild plants surrounding mining wastes. Environmental Pollution 144(1):84-92. 
Crossref
 
Govea-Salas M, Morlett-Chávez J, Rodriguez-Herrera R, Ascacio-Valdés J (2017). Some Mexican Plants Used in Traditional Medicine. In INTECH (Ed.). Aromatic and Medicinal Plants - Back to Nature (1ra ed., pp. 191-200). 
Crossref
 
Granados S, Balcázar N, Guillén A, Echeverri F (2015). Evaluation of the hypoglycemic effects of flavonoids and extracts from Jatropha gossypifolia L. Molecules 20(4):6181-6193. 
Crossref
 
Gutiérrez-Tlahque J, Aguirre-Mancilla CL, Raya-Pérez JC, Ramírez-Pimentel JG, Jiménez- Alvarado R, Hernández-Fuentes AD (2018). Effect of climate conditions on total phenolic content and antioxidant activity of Jatropha dioica Cerv. var. dioica. Ciencia e Investigación Agraria 45(1):70-81. 
Crossref
 
Gutiérrez M, Pando-Moreno M, Jurado E, González-Rodríguez H, Marmolejo JG, Mendoza D (2018). Non-random distribution of biocrust in a natural arid environment in the northern mexican plateau. Applied Ecology and Environmental Research 16(3):2441-2451. 
Crossref
 
Kim J, Jho KH, Choi YH, Nam, SY (2013). Chemopreventive effect of cactus (Opuntia humifusa) extracts: Radical scavenging activity, pro-apoptosis, and anti-inflammatory effect in human colon (SW480) and breast cancer (MCF7) cells. Food and Function 4(5):681-688. 
Crossref
 
Kumar J, Singh SP, Choudhary GK (2016). Pharmacological evaluation of leaves of Jatropha curcas L. for anti-diabetic activity in alloxan induced diabetic rats. Indian Journal of Animal Sciences 86(4):387-391.
 
Latorre D, Latorres F (1977). Plants used by the Mexican Kickapoo Indians. Economic Botany 31:340-357.
Crossref
 

Manzanero-Medina GI, Alejandro FM, Sandoval-Zapotitla E, Bye-Boettler R (2009). Etnobotánica de Siete Raíces Medicinales en el mercado de Sonora de la Ciudad de México. Polibotánica 27:191-228. 

View

 
Martínez N, Almaguer G, Vázquez-Alvarado P, Figueroa A, Zúñiga C, Hernández-Ceruelos A (2014). Análisis fitoquímico de Jatropha dioica y determinación de su efecto antioxidante y quimioprotector sobre el potencial genotóxico de ciclofosfamida, daunorrubicina y metilmetanosulfonato evaluado mediante el ensayo cometa. Boletín Latinoamericano y Del Caribe de Plantas Medicinales y Aromáticas 13(5):437-457.
 
Melchor-Martínez EM, Silva-Mares DA, Torres-López E, Waksman-Minsky N, Pauli GF, Chen SN (2017). Stereochemistry of a Second Riolozane and Other Diterpenoids from Jatropha dioica. Journal of Natural Products 80(8):2252-2262. 
Crossref
 

Mendoza-Moreno JC (2000). Cuantificación de Taninos condensados de corteza y madera en la especie Sangre de Drago (Jatropha dioica). 

View

 
Ocegueda S (2005). Plantas utilizadas en la medicina tradicional y su identificación científica. BioDiversitas. México.
 
Oliveira Simone GD, Nascente PS, Escareño JH., Carvalho RV, Piva E, Lund RG (2013). Evaluation of anti-Candida activity and cytoxicity of Jatropha dioica Cervical extracts. African Journal of Microbiology Research 7(30):3903-3907. 
 
Oropeza Dominguez I (2006). Estudio etnobotánico de plantas medicinales en Tunititlán, Hidalgo y evaluación antibacteriana de la especie vegetal más empleada en el tratamiento de enfermedades de etiología infecciosa. Universidad Autonoma Metropolitana.
 
Pabón LC, Hernández-Rodríguez P (2012). Importancia química de Jatropha curcas y sus aplicaciones biológicas, farmacológicas e industriales. Revista Cubana de Plantas Medicinales 17(2):194-209. 
 
Patil RN, Patil RY, Ahirwar B, Ahirwar D (2011). Evaluation of antidiabetic and related actions of some Indian medicinal plants in diabetic rats. Asian Pacific Journal of Tropical Medicine 4(1):20-23. 
Crossref
 
Perroni Y, García-Oliva F, Souza V (2014). Plant species identity and soil P forms in an oligotrophic grassland-desert scrub system. Journal of Arid Environments 108:29-37. 
Crossref
 
Pertino M, Rodríguez JA, Theoduloz C, Razmilic I, Schmeda-Hirschmann G (2006). Gastroprotective activity and cytotoxic effect of cyperenoic acid derivatives. Journal of Pharmacy and Pharmacology 58(11):1507-1513. 
Crossref
 
Rahuja N, Mishra A, Maurya R, Srivastava MN, Tamrakar AK, Jain SK, Srivastava AK (2013). Antidiabetic and hypolipidemic activity in stem of Jatropha gossypifolia L. International Journal of Pharmacy and Pharmaceutical Sciences 5(Suppl. 4):706-715.
 

Ramírez Moreno A, Serrano Gallardo LB, Barragán Ledezma L, Barragán Ledezma E, Pérez- Vertti A, Daniel R, Delgadillo Guzmán D (2016). Determinación de los compuestos polifenólicos en extractos de Jatropha dioica y su capacidad antioxidante. Revista Mexicana de Ciencias Farmacéuticas 47(4):42-47. 

View

 
Razo Rodríguez C, Alvarado Bárcenas E (2014). Captosan tónico capilar de sangregado (Jatropha dioica). Jóvenes En La Ciencia 1(1):493-497.
 
Sahu J, Sen P, Choudhury MD, Dehury B, Barooah M, Modi MK, Talukdar A (2014). Rediscovering Medicinal Plants' Potential with OMICS: Microsatellite Survey in Expressed Sequence Tags of Eleven Traditional Plants with Potent Antidiabetic Properties. OMICS: A Journal of Integrative Biology 18(5):298-309.
Crossref
 
Sati P, Dhyani P, Bhatt ID, Pandey A (2019). Ginkgo biloba flavonoid glycosides in antimicrobial perspective with reference to extraction method. Journal of Traditional and Complementary Medicine 9(1):15-23. 
Crossref
 
Serrano-Gallardo LB, Castillo-Maldonado I, Borjón-Ríos CG, Rivera-Guillén MA, Morán-Martínez J, Téllez-López MA (2017). Antimicrobial activity and toxicity of plants from northern Mexico. Indian Journal of Traditional Knowledge 16(2):203-207.
 
Sevilla-Asencio OA, Dublán-García O, Gómez-Oliván LM, López-Martínez LX (2013). Actividad inhibitoria sobre α-glucosidasa y α-amilasa de extractos acuosos de algunas especias utilizados en la cocina mexicana. CienciaUAT 8(1):42-47. 
Crossref
 
Sharma SK, Singh H (2012). A review on pharmacological significance of genus Jatropha (Euphorbiaceae). Chinese Journal of Integrative Medicine 18(11):868-880. 
Crossref
 
Silva-Belmares Y, Rivas-Morales C, Viveros-Valdez E, Cruz-Galicia MG, Carranza-Rosales P (2014). Antimicrobial and Cytotoxic Activities from Jatropha dioica Roots. Pakistan Journal of Biological Sciences 17(5):748-750. 
Crossref
 
Silva-Mares D, Torres-López E, Rivas-Estilla AM, Cordero-Pérez P, Waksman-Minsky N, Rivas-Galindo VM (2013). Plants from northeast Mexico with anti-HSV activity. Natural Product Communications 8(3):297-298. 
Crossref
 
Terrazas-Hernández J, Santos-López E, Cariño-Cortés R, Jiménez-Alvarado R, López-Palestina C, Hernández-Fuentes A (2018). Effects of Sterilization on Bioactives of Jatropha dioica and Opuntia oligacantha Extracts, and on Antimicrobial Capacity against Streptococcus mutans. Applied Sciences 8(12):1-15. 
Crossref
 
UNAM (2010). Biblioteca digital de la medicina tradicional mexicana. 
 
Valenzuela Soto R (2014). Compuestos activos con capacidad hipoglucemiante en Cnidoscolus chayamansa (Chaya), Euphorbia prostrata (Hierba de la Golondrina) y Jatropha dioica (Sangre de Drago). Universidad Autónoma de Nuevo León.
 
Vargas-Segura AI, Silva-Belmares SY, Segura-Ceniceros EP, Ascacio-Valdés JA, Méndez- González L, Ilyina A (2018). Screening and characterization of medicinal plants extracts with bactericidal activity against Streptococcus mutans. Natural Product Research, pp. 1-5. 
Crossref
 
Villanueva-Ibáñez M, González Montes de Oca R, Camargo Pérez VP, Olvera-Venegas PN, Martínez Pérez AI, Vera Cárdenas EE, Flores-González MA (2018). Microstructural Characterization of Biosynthesized ZnO Nanostructures Using Jatropha dioica Aqueous Extract. Microscopy and Microanalysis 24(Suppl. 1):1422-1423. 
Crossref
 
Wong-Paz JE, Castillo-Inungara ML, López-López LI, Contreras-Esquivel JC, Nevárez- Moorillon GV, Aguilar CN (2010). Jatropha dioica: Fuente potencial de antimicrobianos. Revista Científica de La 178 Afr. J. Pharm. Pharmacol. Universidad Autónoma de Coahuila 2(4):1-5. 
 
Wong-Paz JE, Contreras-Esquivel JC, Muñiz-Marquez D, Belmares R, Rodriguez R, Flores P, Aguilar CN (2014). Microwave-assisted extraction of phenolic antioxidants from semiarid plants. American Journal of Agricultural and Biological Science 9(3):299-310.
Crossref
 
Wong-Paz JE, Muñiz-Márquez DB, Aguilar-Zárate P, Rodríguez-Herrera R, Aguilar CN (2014). Microplate quantification of total phenolic content from plant extracts obtained by conventional and ultrasound methods. Phytochemical Analysis 25(5):439-444. 
Crossref
 
Wong-Paz JE, Contreras-Esquivel JC, Rodríguez-Herrera R, Carrillo-Inungaray ML, López KI, Nevárez-Moorillón GV, Aguilar CN (2015). Total phenolic content, in vitro antioxidant activity and chemical composition of plant extracts from semiarid Mexican region. Asian Pacific Journal of Tropical Medicine 8(2):104-111. 
Crossref
 
Wong Paz JE, Muñiz Márquez DB, Martínez Ávila GCG, Belmares Cerda RE, Aguilar CN (2015). Ultrasound-assisted extraction of polyphenols from native plants in the Mexican desert. Ultrasonics Sonochemistry 22:474-81. 
Crossref