African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2142

Table of Content: 29 May, 2012; 6(20)

May 2012

Study on transcription regulation network in rheumatoid arthritis via bioinformatics analysis

Rheumatoid arthritis (RA) is a systemic, inflammatory autoimmune disease with irreversible joint destruction. It is a form of autoimmunity, however, its cause is incompletely known. The objective of this study was to identify potential transcription regulation between transcription factors and differentially expressed genes in RA by using the microarray data and transcriptional network analysis. In addition, their...

Author(s): Jie Chen, Jun Xia,Siqun Wang, Yibing Wei, Jianguo Wu, Gangyong Huang, Feiyan Chen and Jingcheng Shi    

May 2012

Effect of Nigella sativa seeds on reproductive system of male diabetic rats

This study aims to investigate the effects of Nigella sativa seeds (NSS) on fertility of male diabetic rats. Animals were divided into 3 groups, one group was kept as control and the two other were rendered diabetic by alloxan (120 mg/kg b.wt). One group was left as diabetic control (Diab) and the second were treated (Diab+N) with 2% of NSS in diet for 30 days. Blood samples were collected for glucose and...

Author(s): Zohra Ghlissi, Khaled Hamden, Mongi Saoudi, Zouheir Sahnoun, Khaled Mounir Zeghal, Abdelfattah El Feki and Ahmed Hakim    

May 2012

Nicotine decreased expression of fibronectin in lung parenchyma newborn

Smoking during pregnancy may impair pulmonary function in infants and children. Nicotine is one of the chemical substances with high level of toxicity. It crosses the placenta and accumulates in the developing organs of fetus. Previous investigations indicated that maternal nicotine exposure induces abnormal collagen IV expression and causes defects in bronchopulmonary development. In this study, the effect of...

Author(s): Mahdi Shariati kohbanani, Mohammad Reza Nikravesh, Mehdi Jalali, Alireza Fazel, Alireza Ebrahimzadeh and Mojtaba Sankian    

May 2012

Erythropoietin does not ameliorate limb schemia/reperfusion injury in rabbits

The effect of erythropoietin on ischemic-reperfusion (I/R) injury in the limbs has not been hitherto investigated. Therefore, we aimed at determining whether erythropoietin has protective effects on the limb I/R injury in rabbits. Twenty adult New Zealand white rabbits underwent clamping of the left femoral artery for 6 h. The rabbits were randomly divided into two groups: Group I (limb I/R) received subcutaneous saline...

Author(s): Shahryar Hashemzadeh, Khosrow Hashemzadeh, Ali Ranjbari, Monireh Halimi, Rasoul Estakhri, Raheleh Aligholipour and Kamyar Ghabili    

May 2012

The effect of competition on gamma-glutamyl transferase, creatinine and protein levels of taekwondo players

Post-exercise proteinuria and increased urinary gamma-glutamyl transferase (GGT) levels can be predictive of exercise induced renal damage. In the literature, numerous studies exist on exercise induced proteinuria, but studies investigating the effects of exercise on urinary GGT levels are quite few in martial arts. The purpose of this study was to determine that changes in serum and urinary GGT activity and creatinine...

Author(s): Banu Ayca, Azize Sener, Nusret Ramazanoglu and Rabia Oba    

May 2012

Analgesic and anti-inflammatory effect of whole Ageratum conyzoides and Emilia sonchifolia alcoholic extracts in animal models

This study was designed to investigate the analgesic and anti-inflammatory effects ofAgeratum conyzoides and Emilia sonchifolia alcoholic extracts in animal models. Analgesic effects have been investigated in acetic acid induced writhing model and formalin induced licking model of Swiss albino mice. Anti-inflammatory effect was investigated in carrageenan induced anti-inflammatory paw edema model of...

Author(s): Md. Atiar Rahman, Nasima Akter, Hasanur Rashid, Nazim Uddin Ahmed, Nazim Uddin and Md. Shahidul Islam    

May 2012

Physical and chemical analysis of some imported essential oils in the Sudanese market

A market survey in Sudan indicated the growing trend of import of essential oils as crude raw materials or in a form of semi-finished or finished products and commodities. Quality control and assessment of the imported essential oils need to be promoted bearing in mind the research and development in this field. The main objectives of the present paper were to evaluate some of these imported essential oils namely: mint...

Author(s): Samya Mohy Eldin Osman, Humeida Ali El-Obeid and Saad Mohamed Hussein Ayoub    

May 2012

A comparative study on the status of Zn and Cu in diabetic and non diabetic males in Punjab, Pakistan

Minerals play a considerable role in the prolongation of all biological and psychological processes in the body. The present study was aimed to determine and to compare the concentration of zinc and copper in the serum samples of diabetic and non diabetic males of different age groups, that is, between one to seventy five years. Fasting blood samples of diabetic males as well as of non diabetics of selected age groups...

Author(s): Anbreen Anjum, Muhammad Yousaf, Muhammad Zuber, Tanveer Hussain Bukhari, Ameer Fawad Zahoor, Zafar Iqbal Khan, Shazia Naheed, Kulsoom Ghulam Ali,  Bushra Purveen, Kafeel Ahmad, Muhammad Khalid Mukhtar, Saira Hina, Sajjad Ahmad, Muhammad Umair Tariq and Ghulam Hussain    

May 2012

Determination of heavy metal concentration of different traditional medicine formulations available at the East Coast Region of Malaysia

Traditional medicines (TM) of herbal origin have been increasingly getting popular in the last few decades. In Malaysia, a significant number of people consume locally available traditional medicine for their health care needs. Due to the wide use of herbal medicines, regulatory authorities express concern about the safety of using these products. Heavy metal content of the medicinal formulation is one of them. Exposure...

Author(s): A. B. M. Helal Uddin, Reem S. Khalid and S. A. Abbas    

May 2012

Anti-obesity effects of mogrosides extracted from the fruits of Siraitia grosvenorii (Cucurbitaceae)

In this study, total mogrosides extracted from Siraitia grosvenorii as well as, mogrosides V and IV were tested for their effects on pancreatic lipase in vitro. The body weight and food intake, abdominal and epididymal fats weight, and hepatic triacylglycerol (TG) and total cholesterol (TC) contents were evaluated using male C57BL/6 mice fed with a high fat diet (HF) with or without different...

Author(s): Bai-Shen Sun, Yan-Ping Chen, Yi-Bo Wang, Shou-Wan Tang, Fu-You Pan, Zheng Li and Chang-Keun Sung