October 2012
Anti-inflammatory effect of Papenfussiella kuromo in lipopolysaccharide or peptidoglycan-induced macrophage cells
Marine bioresources are known to be attractive as they sometimes contain new compounds showing several kinds of different bioactivities which are not possible in land plants. Brown algae, Papenfussiella kuromo is widely distributed in Korea and Japan. However, no studies have been conducted to evaluate the anti-inflammatory activities of the extract of P. kuromo. We studied its anti-inflammatory effect in...
October 2012
The effect of salidroside on inflammatory factors in rats with hemisection-induced spinal cord injury
The effect of salidroside on inflammatory factors in rats with hemisection-induced spinal cord injury (SCI) was studied. The Sprague-Dawley (SD) rats were divided into six groups: Sham control group, SCI model group, the methylprednisolone sodium succinate (MPSS) treatment group, the salidroside-low dosage treatment group, the salidroside-moderate dosage treatment group and the salidroside-high dosage treatment group....
October 2012
Chemical assessment of wild Paris rhizome from Southwest China
Chonglou is a well known traditional Chinese medicine for anti-cancer and traumatic injuries. The major sources of Chonglou are from genus Paris. The present investigation aimed to determine contents of active steroidal saponins in Paris plants collected from different locations of Southwest China. The results showed that polyphyllin I and polyphyllin VII could be detected in almost all samples. However,...
October 2012
Antimicrobial activity of Melampyrum cristatum, Melampyrum bihariense and Melampyrum arvense tinctures
The infections with bacteria and fungi resistant to existing chemotherapeutic drug have become a serious problem in the whole world, which leads to the continuous need to develop new antimicrobial agents. The plants extracts may represent future solutions against these pathogens. The purpose of this study was to determine the antibacterial and antifungal activity of Melampyrum cristatum, Melampyrum...
October 2012
Methylation in non-coding sequences may be related to the tolerance of common carp to cadmium
In order to understand the molecular mechanism underlying the tolerance of common carp to cadmium (Cd), we exposed three-month old common carp (Cyprinus carpio var. Jian) to different concentrations of Cd2+ (0.005, 0.05, 0. 5 and 5 mg/L) for 2 days. Results showed that no individual died during the exposure. Furthermore, we used 10 random amplified polymorphic DNA (RAPD) primers to detect the difference in the...
October 2012
MG132 reduces the pro-inflammatory effect of cyclooxygenase 2 (COX-2) on glomerular mesangial cells
Cyclooxygenase 2 (COX-2) over expression is involved in the proliferation of mesangial cells in the pathogenesis of glomerulonephritis, and nuclear factor kappa B (NF-κB) signaling participates in the induction of COX-2 gene expression in these cells. This study explores the effect of MG132, a NF-κB proteasome inhibitor, on the pro-inflammatory effect of glomerular COX-2 gene overexpression. A...
October 2012
Expression of interleukin 17 and IgE, and its significance in patients with bronchial asthma
To investigate the expression and its significance of interleutin-17 (IL-17) and immunoglobulin E (IgE) in patients with bronchial asthma, sixty adult patients with bronchial asthma and 30 healthy human control were sequentially enrolled in this study. The production of IL-17 was measured by enzyme-linked immunosorbent assay (ELISA) and fluorescent quantitative polymerase chain reaction (qPCR), respectively. The...
October 2012
Clinical management of lipid profile, renal and liver function versus HbA1c profile in diabetes affected patients of Vellore, Tamil Nadu, India
The aim of this study is to examine clinical management of lipid profile, renal and liver function versus HbA1c value correlation in diabetic population of Vellore district in South India. A total of 1300 cases from three different diabetic clinics in Vellore were taken for the study. 25% of populations were selected as control.Parameters such as age, sex, fasting blood glucose, postprandial blood glucose, lipid...
October 2012
Antinociceptive and neuropharmacological activities of ethanolic extract of the fruits of Ficus hispida Linn.
The crude ethanolic extract of the fruits of Ficus hispida Linn. (Family: Moraceae) growing in southeast part of Bangladesh has been evaluated for its possible antinociceptive and neuropharmacological properties. The ethanolic extract of the fruits of F. hispida exhibited statistically significant (p < 0.001) writhing inhibition in acetic acid-induced writhing model in white albino...
October 2012
Hypoglycemic and hematological effects of aqueous extract of Thymus serpyllum Linn. in alloxan-induced diabetic rabbits
This study was designed to evaluate the effect of aqueous extract of Thymus serpyllum Linn. on blood glucose level, body weight, and some hematological parameters of alloxan induced diabetic rabbits for a period of one month. It was found that the aqueous extract significantly (P < 0.01) reduced the blood glucose level in diabetic rabbits. This decrease in blood glucose level was comparable to the effect of...
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