African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2184

Table of Content: 8 December, 2011; 5(21)

December 2011

BS and BS-contained rat serum’s anticancer activities

The aim of the study is to evaluate the anticancer potential of BS. Cytotoxicity assays was carried out to test the activity of BS against mouse model cancer and to test the activity of BS-contained serum against SGC; the human gastric cancer cell. Cytotoxicity assays showed that BS has a wide range of antitumor spectrum. Activity evaluation toward a set of BS-contained-serum that was derived from rat, at different...

Author(s): Chen-Xiaoxi

December 2011

Clinical and radiological results of posterior instrumentation without fusion for thoracolumbar fractures

A retrospective study of clinical and radiological results of nonfusion operative treatment for thora-columbar fractures. In this study, we aimed to demonstrate that fusion was not always required in the surgical treatment with posterior instrumentation for thoracolumbar vertebral fractures and to show the success of surgical treatment without fusion. Fusion was added considering failure of the implant and inability to...

Author(s): Serdar Sargın, Bekir Yavuz Uçar, Serdar Necmioğlu, Mehmet Bulut and Mehmet Gem

December 2011

The cardiovascular inhibition functions evoked by salusin β within the caudal ventrolateral medulla are mediated by muscarinic receptors mechanism

Salusin α and salusin β are newly found bioactive peptides of 20 and 28 amino acid respectively, distributed widely in hematopoietic system, endocrine system and the central nervous system. Our present study is to determine the cardiovascular functions of salusin β within the caudal ventrolateral medulla (CVLM) of rats. Unilateral microinjection of the artificial cerebrospinal fluid (aCSF) into the CVLM...

Author(s): Lei YANG, Xiao-Yun LI, Ying-Li ZHEN, Yan LU, Nong CAO and Chen ChAI

December 2011

Wound healing activity of flaxseed Linum usitatissimum L. in rats

Wound healing is a complex process which requires special factors and condition. Drugs which accelerate wound healing are expanded, particularly herbal drugs which are mainly safe and effective. Hence, the present study was conducted to evaluate wound healing activity of flaxseed oil on experimentally induced incision wound. The therapeutic ointments were prepared according to two concentrations, 0.75 and 1.5%, and were...

Author(s): Mohammad Reza Farahpour, Human Taghikhani, Mostafa Habibi and Mohammad Amin Zandieh

December 2011

Protective effect of an aqueous extract of 3 Ballerina against the action of the stannous chloride in Escherichia coli BW9091

3 Ballerina (3B) is a natural formula that has medicinal properties. Scientific information about this formula is not found in PubMed, and this fact has stimulated investigations about its biological effects. Stannous chloride (SnCl2) is present in many of our daily life activities and is capable to generate free radicals. The exonuclease III (xthA) protein is a member of the base excision repair, a key repair...

Author(s): Pinto N. S., Pereira M. O., Carmo F. S., Diniz C. L., Medeiros A. C., Santos-Filho S. D. and Bernardo-Filho M.,

December 2011

Study of cutaneous wound healing in rats treated with Lactobacillus plantarum on days 1, 3, 7, 14 and 21

Probiotics are microorganisms in the gastrointestinal tract that help the immune system and reduce inflammation. The beneficial effects of these bacteria on ulcer healing have been proved but little research has been done in the field of cutaneous wound healing. Therefore, the purpose of this experiment is to study the effect of Lactobacillus plantarum on cutaneous wound healing. Some strains...

Author(s): Heydari Nasrabadi, M., Tajabadi Ebrahimi, M., Dehghan Banadaki, Sh., Torabi Kajousangi, M. and Zahedi, F.

December 2011

Synthesis and characterization of ordered mesoporous silica nanoparticles with tunable physical properties by varying molar composition of reagents

Mesoporous silica nanoparticles (MSN) with tunable physical and surface properties would find application in various biotechnological and biomedical fields. In this study, a series of MSN with varied physical properties were synthesized via liquid crystal templating (LCT) mechanism by varying the molar concentrations of the reagents. Characterization of the prepared materials was done by scanning electron microscopy...

Author(s): Harrison Wanyika, Erastus Gatebe, Paul Kioni, Zhiyong Tang and Yan Gao

December 2011

Evaluation to the antioxidant activity of total flavonoids extract from Syzygium jambos seeds and optimization by response surface methodology

The purpose of this work was to assess the antioxidant activity of total flavonoids extract fromSyzygium jambos seeds (TFSJ). Response surface methodology was employed to optimize the main extraction conditions including extraction time, ethanol concentration and solid-liquid ratio. The effect of TFSJ on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, 2,2-azino-bis(3-ethyl-benzthiazoline-6-sulfonic acid)...

Author(s): Ni Zheng, Zhaoyu Wang, Feng Chen and Jingming Lin