July 2013
Developmental effects of extracts produced by some newly isolated Actinobacteria on the heart of Zebra fish (Danio rerio) embryos
Most actinomycete species have the capability to synthesize many different biologically active secondary metabolites such as antibiotics, herbicides, pesticides, anti-parasitic and enzyme inhibitors. The main focus of the present study was to isolate some new actinobacterial strains from the Saudi habitats and study the biological effects of their secondary metabolites on the heart development of the zebra fish embryos...
July 2013
Biological activities of the hydro-alchoholic and aqueous extracts of Achillea biebersteinii Afan. (Asteraceae) grown in Jordan
Aqueous and hydro-alcoholic extracts of Achillea biebersteinii Afan. (Asteraceae) grown in Jordan were screened for their antioxidant, antibacterial and antiplatelet efficacy. Total phenols and flavonoids were determined colorimetrically. The radical scavenging activities were evaluated using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical...
July 2013
Nutritional composition, vitamins, minerals and toxic heavy metals analysis of Digera muricata (L.) Mart.: A wild edible plant from Peshawar, Pakistan
This study was aimed to assess the nutritional potential of an unexplored wild edible plant,Digera muricata (L.) Mart. commonly used as food in Peshawar, Khyber Pakhtunkhwa, Pakistan. The nutritional, vitamins, minerals and trace elements were investigated, using standard methods of Association of Official Analytical Chemists (AOAC). Nutritional assessment included determination of moisture, ash, lipid, fiber,...
July 2013
Effect of Ocimum basilicum on ovary tissue histopathology after exposure to electromagnetic fields (EMF) in rats
Plants continue to be a major source of medicines, as they have been throughout human history. Ocillium basilicum has been used since ancient times as a medicine and food and it is known that the antioxidant effect of O. basilicum is beneficial to protect tissue and decreasing carcinogeniceffect of electromagnetic field (EMF), so it was hypothesized that this herb might also provide protection to...
July 2013
Formulation of solid dispersion and surface solid dispersion of nifedipine: A comparative study
In this study, an attempt was taken to enhance the solubility and dissolution characteristics of nifedipine, a poorly water soluble calcium channel blocking agent, by preparing solid dispersions (SD) with water soluble carriers; Poloxamer 407, HPMC 5 cPs, polyethylene glycol (PEG) 4000 and 6000 and surface solid dispersions (SSD) with insoluble carriers; sodium starch glycolate (SSG) and croscarmellose sodium...
July 2013
In vitro antimicrobial activity of Syzygium cumini fruit peel and identification of anthocyanins
The present investigation evaluated the antimicrobial potential of Syzygium cumini (SC) fruit peel against fourteen microorganisms and identified major anthocyanins. Methanol, ethyl acetate and dichloromethane extracts of shade dried SC fruit peel were screened for antimicrobial effects using disc diffusion and minimum inhibitory concentration (MIC) methods. Methanol extract showed maximum antimicrobial...
July 2013
Oestrogenic properties of the ethanolic extract of Fernandoa adolfi friderici (Bignoniaceae) stem bark
Fernandoa adolfi friderici is used traditionally to treat menopause related symptoms. The effects of the ethanolic extract of this plant in ovariectomized (OVX) rats were investigated. 40 of 50 rats were OVX and separated into four groups of 10 each. 84 days after ovariectomy, animal groups were started on one of four treatments: ethanol/0.09% NaCl (control group), oestrogen, extracts of F. adolfi...
July 2013
Antihyperlipidemic effect of ambrex, a polyherbal formulation against experimentally induced hypercholesterolemia in rats
Ambrex, a polyherbal formulation was tested for its antihypercholesterolemic effect against experimentally induced hypercholesterolemia in rats. Alteration in the levels of serum marker enzymes, alanine amino transferase (ALT), aspartate amino transferase (AST), lactate dehydrogenase (LDH), alkaline phosphatase (ALP) and general biochemical parameters glucose, protein, urea and creatinine were tested in both treated and...
July 2013
Novel controlled release of antihypertensive drug: preparation, in-vitro and in-vivo evaluation
The objective was to control the release of diltiazem HCl. Emulsion solvent evaporation technique was applied to encapsulate diltiazem HCl using ethyl cellulose or Eudragit RS100. The prepared microspheres were characterized concerning entrapment efficiency;micromeritics properties and surface morphology using SEM and mixed with carbopol, hydroxypropyl methyl cellulose, or chitosan in different ratios....
July 2013
Preventive effects of silymarin in retinal intoxication with methanol in rat: Transmission electron microscope study
The aim of this study was to investigate the ultra-structure of the photoreceptor layer of male rats under the effect of methanol intoxication and protective effect of silymarin against the methanol toxicity. Fifteen adult male rats were divided into three groups: Control group, Experimental group I (received 4g/kg methanol by intraperitoneal injection for five days), Experimental group II (received 4 g/kg methanol by...
July 2013
Influence of serpentine soils on the flavonoid content of Hypericum populations growing in Bulgaria
The effect of environmental factors on the production of secondary metabolites by plants has attracted a considerable amount of attention. Most species populations growing on serpentine soils are adapted to these special edaphic conditions in different ways. In this study we investigated the flavonoid content in Bulgarian Hypericum populations from five Hypericumspecies (H. cerastoides, H....
Advertisement
Advertisement
