November 2011
A review on Hyssopus officinalis L.: Composition and biological activities
Hyssopus officinalis L. (Hyssop) is one of the most popular herbal preparations, mainly distributed in the East Mediterranean to central Asia. The plant has been used traditionally for medicinal purposes; generally, these therapeutic uses and health benefits of hyssop are largely based on folklore rather than on scientific substantiation, making it a good candidate to gather documentations, including the...
November 2011
Identification of phenolic compounds and assessment of in vitro antioxidants activity of 30% ethanolic extracts derived from two Phyllanthus species indigenous to Malaysia
Phenolic compounds were identified in 30% ethanolic extracts derived from Phyllanthus niruri(P. niruri) and Phyllanthus urinaria (P. urinaria) using high performance liquid chromatography (HPLC) assay. In vitro antioxidants activity of the extracts was studied based on total phenolic contents (TPC) using Folin-Ciocalteu reagent and their scavenging activity towards radical...
November 2011
Cultural importance and antibacterial activity of Ziziphus mucronata (Willd.) in the Umlazi community in Durban
The Zulu community of Umlazi, Durban makes extensive use of Ziziphus mucronata (Buffalo thorn) for predominantly cultural purposes. There are many superstitions and beliefs associated with the tree. A validation of its antimicrobial properties from leaf, bark and root extracts were attempted against three Gram positive and three Gram negative bacteria. In addition, an antifungal assay was attempted, using...
November 2011
Altitude-related changes in activities of carbon metabolism enzymes and secondary plant products-menthoforon an active pharmaceutical constituents yield in pippermint (Mentha piperita L. Var. Kukarail)
Activities of some enzymes related to carbon metabolism were studied in different ecotypes of pippermint (Mentha piperita L. Var. Kukarail), growing at 950 and 1,250 m above mean sea level. Activities of peroxidase and superoxide dismutase (SOD) and geranyl pyro phosphate (GPP) are significantly higher in higher altitude cultivated cultivars. The GPP which converts to geranyl geranyl pyro phosphate (GGPP)...
November 2011
Simultaneous determination of gatifloxacin and dexamethasone sodium phosphate in bulk and pharmaceutical formulations by HPLC
A liquid chromatography method was developed and validated for the simultaneous determination of gatifloxacin and dexamethasone sodium phosphate in bulk and pharmaceutical formulations. Optimum separation was achieved in less than 5 min using a C18column (250 × 4.6 mm i.d, 5 µ particle size) by isocratic elution. UV detection was carried out at 254 nm. Developed method was economical in terms of the time...
November 2011
Anti-inflammatory and wound healing activity of Fagonia schweinfurthii alcoholic extract herbal gel on albino rats
Traditionally, a large number of plants are used for treatment of inflammation and wounds. In Asian and African countries Fagonia schweinfurthii (Hadidi) (F. Zygophyllaceae) and the closely related herb, such as Fagonia arabica are traditionally used for treatment of inflammation, open wounds, boils, skin eruptions, allergies, etc. Hence, the present study was conducted to investigate the...
November 2011
The effects of maximal aerobic exercise on cortisol and thyroid hormones in male field hockey players
Some metabolic and endocrine functions might be influenced by exercise and it leads to changed concentrations of hormone secretions in humans. In order to determine the changes of thyroid hormones (THs) related to shuttle run exercise (SRE), 14 field hockey players and their thyroid stimulating hormones (TSH) free T3 (fT3), free T4 (fT4) were included in this study, and cortisol levels were measured...
November 2011
Cationic liposomes as gene delivery system
Delivery of oligonucleotides (ONs) and genes to their intracellular targets is a prerequisite for their successful use in medical therapy. Cationic liposomes are among the most commonly used and promising delivery system for ONs and genes. Cationic-liposomes and their complexes with ON were characterized according to complex size, zeta potential measurements, transmission electron microscope (TEM) and confocal laser...
November 2011
Nitrous oxide versus pethidine with promethasine for reducing labor pain
Systemic opioids are widely used for the relief of labor pain. Self-administered nitrous oxide with concentration of 50% is a new form of analgesia. The aim of this study was to compare the analgesic efficacy and side effects of the patient controlled inhaled nitrous oxide (50% ‘‘Entonox’’) with systemic intramuscular pethidine, in reducing pain during normal vaginal labor in Iranian population....
November 2011
Differential analysis of human kidney stone samples using electrospray ionization mass spectrometry
Kidney stones may be caused by many factors, including ingestion of melamine for a relatively long time. The diagnosis of melamine-induced kidney stones and the understanding of how the melamine is involved in the formation of kidney stones are of practical importance. To establish a sensitive method based on widely used electrospray ionization mass spectrometry (ESI-MS) for diagnosis of melamine-induced kidney stones...
November 2011
Radical scavenging and antioxidant activity of Hibiscus rosasinensis extract
Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. In the present study, the antioxidant properties of crude extract ofHibiscus rosasinensis were examined, using different in vitro analytical methodologies, such as total antioxidant activity determination...
November 2011
Therapeutic monitoring of isoniazid, rifampicin, ethambutol and pyrazinamide serum levels in the treatment of active pulmonary tuberculosis and determinants of their serum concentrations
Inadequate serum levels of antimycobacterial drugs have been associated with treatment failure, relapse and acquired drug resistance as well as high concentrations of these drugs may cause intolerance and toxic effects. We objected in this study to determine serum concentrations of anti-tuberculosis drugs and to know the determinants of their concentrations. Venous blood samples was obtained 2 and 6 h after drug...
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